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Electroacupuncture improves cognitive impairment after subarachnoid hemorrhage in rats through the PI3K/AKT signaling pathway.
Acupunct Med
January 2025
Combination of Acupuncture and Medicine Innovation Research Center, Shaanxi University of Chinese Medicine, Xianyang, China.
Objective: Cognitive impairment (CI) is highly prevalent in subarachnoid hemorrhage (SAH) patients. The phosphatidylinositol 3-kinase (PI3K)/AKT pathway plays a critical role in neuronal survival in a variety of central nervous system injuries. This study aimed to determine whether electroacupuncture (EA) at and LI20 ameliorates SAH-CI in a rat model and to examine whether it modulates the PI3K/AKT pathway by administering a PI3K inhibitor (LY294002) versus dimethyl sulfoxide (DMSO) vehicle.
View Article and Find Full Text PDFPoints regarding neuroscience-based nomenclature: evaluating its impact on psychiatric residency training.
Int Clin Psychopharmacol
March 2025
Department of Neuroscience, University Psychiatric Center, Catholic University of Leuven, Psychiatry Research Group, Leuven, Belgium.
This study evaluates the impact of neuroscience-based nomenclature (NbN) training on psychiatric residents in Flanders, Belgium. Addressing Zemach et al.'s findings on NbN's potential, we investigated its application in clinical practice.
View Article and Find Full Text PDFNutrition in the critically ill in resource-limited settings/low- and middle-income countries.
Curr Opin Clin Nutr Metab Care
January 2025
Department of Anaesthesiology and Critical Care Medicine, Kepler University Hospital and Johannes Kepler University Linz, Linz, Austria.
Purpose Of Review: To share current concepts and provide an overview of the contextual issues and nutrition practices in critically ill patients in resource-limited settings (RLSs)/low- and middle-income countries (LMICs). Most of the world's population reside in these settings which also carries the greatest burden of critical illness.
Recent Findings: There is a paucity of evidence on nutrition practice in critically ill patients in RLSs and international guidelines are largely based on evidence derived from high-income countries (HICs).
Impact of Imaging and Pharmacological Treatment Strategies in Refractory Ventricular Tachycardia in Critically Ill Patients: A Systematic Review.
Cureus
December 2024
Medicine, Universidad Santiago de Cali, Cali, COL.
Ventricular tachycardia (VT) is a life-threatening arrhythmia often leading to sudden cardiac death, particularly in critically ill patients. Refractory VT, characterized by recurrent episodes requiring intervention, poses unique challenges for management, necessitating advanced diagnostic and therapeutic strategies. This systematic review evaluates the impact of imaging and pharmacological treatments in managing refractory VT in critically ill patients.
View Article and Find Full Text PDFAssessment of the Accuracy of Ultrasonographically Measured Optic Nerve Sheath Diameter as a Surrogate for the Detection of Intracranial Hypertension Compared to Optic Nerve Sheath Diameter Measured by MRI: A Prospective Observational Study.
Cureus
December 2024
Anaesthesiology and Critical Care, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.
Background: Ultrasonographic measurement of optic nerve sheath diameter (ONSD) has been proposed as a non-invasive, bedside method to detect raised intracranial pressure (ICP) in various clinical settings. We aimed to correlate the ONSD obtained by ultrasonography (USG) with the ONSD obtained by magnetic resonance imaging (MRI) and to find its measurement accuracy.
Methodology: A prospective double-blind study was carried out by performing ocular ultrasounds on 32 patients with clinical features of intracranial hypertension.
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