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Lateral flow assay with automatic signal amplification based on delayed substrate release.
Talanta
January 2025
State Key Laboratory of Food Science and Resources, Jiangnan University, Lihu Road 1800, Wuxi, 214122, PR China; School of Food Science and Technology, Jiangnan University, Lihu Road 1800, Wuxi, 214122, PR China; International Joint Laboratory on Food Safety, Jiangnan University, Lihu Road 1800, Wuxi, 214122, PR China.
The low sensitivity of Lateral flow assay (LFA) limits its application in rapid detection for trace targets. LFAs with nanozyme (nanozyme-LFA) as signal labels have demonstrated excellent performance in point of care testing (POCT). However, additional operational steps for substrate catalysis in nanozyme LFA are required, which makes the nanozyme-LFA operation complicated.
View Article and Find Full Text PDFHighly parallel simulation tool for the design of isotachophoresis experiments.
Anal Chim Acta
February 2025
Department of Mechanical Engineering, Stanford University, 488 Escondido Mall, Stanford, CA, 94305, USA. Electronic address:
Background: Isotachophoresis (ITP) is a well-established electrokinetic method for separation and preconcentration of analytes. Several simulation tools for ITP have been published, but their use for experimental design is limited by the computational time for a single run and/or by the number of conditions that can be investigated per simulation run. A large fraction of the existing solvers also do not account for ionic strength effects, which can influence whether an analyte focuses in ITP.
View Article and Find Full Text PDFA survey of NHS nurses' delivery of treatments to prevent recurrence of venous leg ulcers.
Int Wound J
January 2025
Division of Psychology and Mental Health, School of Health Sciences, University of Manchester, Manchester, UK.
Preventing recurrence of venous leg ulcers can be achieved through strongest tolerated compression and endo-venous ablation surgery, but it is not clear how often this is done in practice. This study explores (1) nurses' awareness of strongest tolerated compression and endo-venous ablation surgery as prophylactic treatments for venous leg ulcer, (2) how often these treatments are offered, and (3) assessment of the barriers and enablers to deploying those treatments using the capabilities, opportunities and motivations model of behaviour change. An online cross-sectional survey was conducted among nurses who treat and manage venous leg ulcers across the United Kingdom.
View Article and Find Full Text PDFIntermodulation frequencies reveal common neural assemblies integrating facial and vocal fearful expressions.
Cortex
December 2024
Institute of Research in Psychology (IPSY) & Institute of Neuroscience (IoNS), Louvain Bionics Center, University of Louvain (UCLouvain), Louvain-la-Neuve, Belgium; School of Health Sciences, HES-SO Valais-Wallis, The Sense Innovation and Research Center, Lausanne & Sion, Switzerland. Electronic address:
Effective social communication depends on the integration of emotional expressions coming from the face and the voice. Although there are consistent reports on how seeing and hearing emotion expressions can be automatically integrated, direct signatures of multisensory integration in the human brain remain elusive. Here we implemented a multi-input electroencephalographic (EEG) frequency tagging paradigm to investigate neural populations integrating facial and vocal fearful expressions.
View Article and Find Full Text PDFDevelopment of Automatic Method for Glucose Detection Based on Platinum Octaethylporphyrin Sol-Gel Film with Long-Term Stability.
Sensors (Basel)
December 2024
Department of Physics, Northeast Forestry University, Harbin 150040, China.
In this study, an approach has been proposed in response to the urgent need for a sensitive and stable method for glucose detection at low concentrations. Platinum octaethylporphyrin (PtOEP) was chosen as the probe and embedded into the matrix material to yield a glucose-sensing film, i.e.
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