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Nuclear factor I-C regulates intramembranous bone formation via control of FGF signalling.
Heliyon
January 2025
Department of Oral Histology-Developmental Biology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea.
Our previous studies indicate that NFI-C is essential for tooth root development and endochondral ossification. However, its exact role in calvarial intramembranous bone formation remains unclear. In this study, we demonstrate that the disruption of the gene leads to defects in intramembranous bone formation, characterized by decreased osteogenic proliferative activity and reduced osteoblast differentiation during postnatal osteogenesis.
View Article and Find Full Text PDFHealing the Open Apex: A Case Report on Innovative Apexogenesis of a Maxillary Molar Using Bio-C Repair.
Cureus
December 2024
Department of Conservative Dentistry and Endodontics, The Oxford Dental College, Bengaluru, IND.
Preserving pulp vitality in developing permanent teeth is paramount. This approach facilitates continued root formation, ultimately leading to apical closure, enhanced root strength, and improved overall tooth integrity. This case report details the management of a 17-year-old female patient presenting with dental caries on the right permanent maxillary molar.
View Article and Find Full Text PDFRobot-assisted Endodontic Retreatment: A Case Report with Clinical Considerations.
J Endod
January 2025
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China; Department of Cariology and Endodontics, School and Hospital of Stomatology, Wuhan University, Wuhan, China. Electronic address:
Introduction: Fiber posts present significant challenges for nonsurgical endodontic retreatment, as improper removal may result in iatrogenic root perforation or even root fracture. Recently, robotic technology has attracted considerable attention in dentistry and active dental robotic (ADR) systems can perform procedures based on preset instructions, minimizing reliance on the dentist's experience. This case report describes the application of an ADR system for fiber post removal through an existing zirconia crown.
View Article and Find Full Text PDFAssessing Endodontic Treatment Feasibility for Cracked Teeth using Quantitative Light-induced Fluorescence: A Retrospective Clinical Study.
J Endod
January 2025
Department of Conservative Dentistry and Oral Science Research Center, Gangnam Severance Hospital, Yonsei University College of Dentistry, 211 Eonjuro, Gangnamgu, Seoul 06273, Korea. Electronic address:
Introduction: Cracked teeth present diagnostic and treatment challenges due to their complex etiology and uncertain prognoses. This study evaluated the potential of Quantitative Light-induced Fluorescence (QLF) technology for diagnosing cracked teeth and its utility in predicting the need for root canal treatment (RCT).
Methods: A total of 207 cracked teeth from 149 patients diagnosed between April 2019 and April 2023 were analyzed.
Molecular Profiling of Odontoclasts during Physiological Tooth Replacement.
J Dent Res
January 2025
Department of Oral Health Sciences, University of British Columbia, Vancouver, BC, Canada.
The odontoclast is a rarely studied cell type that is overly active in many dental pathologies, leading to tooth loss. It is difficult to find diphyodont mammals in which either physiological or pathological root resorption can be studied. Here we use the adult leopard gecko, which has repeated cycles of physiological tooth resorption and shedding.
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