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Background: Pneumococcal vaccines have been available worldwide since the early 2000s; consequently, few reports exist of poststreptococcal acute glomerulonephritis (PSAGN) or complications of pneumococcal infection. We describe a patient with PSAGN and bacteremia with Streptococcus pneumoniae serotype 22F (not covered by the 13-valent pneumococcal vaccine (PCV 13)).

Case Diagnosis/treatment: A 5-year-old boy received the PCV13 vaccine and was admitted to our hospital with a fever and gross hematuria.

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Serum Endocan Levels in Children with Acute Rheumatic Fever.

Niger J Clin Pract

September 2024

Department of Pediatric Hematology and Oncology, Konya Training and Research Hospital, MD, Konya, Turkey.

Background: Acute rheumatic fever is an immunologically delayed autoimmune sequel of throat infection caused by group A streptococcus. The aim of this study was to evaluate endocan levels in patients with acute rheumatic fever and compare with the control group.

Aim: The aim of this study was to evaluate endocan levels in patients with acute rheumatic fever and compare with the control group.

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[The distribution of biomarkers for Behcet syndrome and their clinical relevance in real-world studies].

Zhonghua Yu Fang Yi Xue Za Zhi

September 2024

Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis, Beijing 100044, China Department of Rheumatology and Immunology, Shijiazhuang People's Hospital, Shijiazhuang 050030, China.

To explore the distribution of different biomarkers for Behcet's syndrome (BS) and their correlation with distinct clinical phenotypes of BS patients in real-world studies. This study was a retrospective cross-sectional study. A total of 483 patients diagnosed with BS in the Department of Rheumatology and Immunology, Peking University People's Hospital from 2019 to 2022 were enrolled.

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Predicting renal damage in children with IgA vasculitis by machine learning.

Pediatr Nephrol

October 2024

Department of Nephrology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang, China.

Background: Children with IgA Vasculitis (IgAV) may develop renal complications, which can impact their long-term prognosis. This study aimed to build a machine learning model to predict renal damage in children with IgAV and analyze risk factors for IgA Vasculitis with Nephritis (IgAVN).

Methods: 50 clinical indicators were collected from 217 inpatients at our hospital.

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Key Clinical Message: Rheumatic heart disease is a preventable disease. Patients may not present with a typical history of sore throat and polyarthritis but may present with Sydenham's chorea. We should not rely completely on clinical findings to rule out carditis.

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