Non traumatic perforations are frequent in Africa South of the Sahara and most often due to salmonellosis. From 50 cases recorded in Dakar, the authors study the main problems raised by diagnosis (specially in non reactive peritonitis requiring iterative controls), surgical tactic and procedure, and intensive care. In 86 p. 100 of the case they report on, the authors performed a suture completed by passive drainage. However, and in spite of the risk of leaking, resection had to be done either immediately or because suture failure. As patients were presented generaly in very bad condition, intensive cares were complex but essential. Death rate ranged between 25 p. 100 and 50 p. 100.
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Br J Surg
September 2022
Department of Economics & Centre for Modern Indian Studies, University of Goettingen, Göttingen, Germany.
Clin J Am Soc Nephrol
September 2021
Merck & Co., Inc., Kenilworth, New Jersey.
Background And Objectives: A reduction in the rate of eGFR decline, with preservation of ≥0.75 ml/min per 1.73 m per year, has been proposed as a surrogate for kidney disease progression.
View Article and Find Full Text PDFPLoS One
April 2012
Department of Global Health, University of Washington, Seattle, Washington, United States of America.
Background: Host genetic factors may be important determinants of HIV-1 sexual acquisition. We performed a genome-wide association study (GWAS) for host genetic variants modifying HIV-1 acquisition and viral control in the context of a cohort of African HIV-1 serodiscordant heterosexual couples. To minimize misclassification of HIV-1 risk, we quantified HIV-1 exposure, using data including plasma HIV-1 concentrations, gender, and condom use.
View Article and Find Full Text PDFPLoS Med
September 2011
Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, Scotland, United Kingdom.
Igor Rudan and colleagues report the results of their consensus building exercise that identified health research priorities to help reduce child mortality from pneumonia.
View Article and Find Full Text PDFClin Infect Dis
September 2011
Center for Infectious Diseases, School of Public Health, Houston, Texas, USA.
Background: Mexico and Central America are important travel destinations for North American and European travelers. There is limited information on regional differences in travel related morbidity.
Methods: We describe the morbidity among 4779 ill travelers returned from Mexico and Central America who were evaluated at GeoSentinel network clinics during December 1996 to February 2010.
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