Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Unanchored simulated treatment comparison on survival outcomes using parametric and Royston-Parmar models with application to lenvatinib plus pembrolizumab in renal cell carcinoma.
BMC Med Res Methodol
January 2025
Clifton Insight, Bristol, UK.
Background: Population-adjusted indirect comparison using parametric Simulated Treatment Comparison (STC) has had limited application to survival outcomes in unanchored settings. Matching-Adjusted Indirect Comparison (MAIC) is commonly used but does not account for violation of proportional hazards or enable extrapolations of survival. We developed and applied a novel methodology for STC in unanchored settings.
View Article and Find Full Text PDFComparative analysis of the physiological and transport functions of various sources of renal proximal tubule cells under static and fluidic conditions in PhysioMimix T12 platform.
Drug Metab Dispos
January 2025
Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas. Electronic address:
In vitro models that can faithfully replicate critical aspects of kidney tubule function such as directional drug transport are in high demand in pharmacology and toxicology. Accordingly, development and validation of new models is underway. The objective of this study was to characterize physiologic and transport functions of various sources of human renal proximal tubule epithelial cells (RPTECs).
View Article and Find Full Text PDFCOMPARING MESH AND COMPRESSOR NEBULIZERS IN PULMONARY FUNCTION TEST IN PEDIATRIC ASTHMA ATTACKS: A DOUBLE-BLIND RANDOMIZED COMPARATIVE CLINICAL TRIAL.
Respir Med
January 2025
Celal Bayar University, Faculty of Medicine, Department Pediatric Allergy and Immunology, Manisa, Turkey.
Objective: Asthma is a prevalent global health issue, especially affecting children in numerous countries. Our study aimed to determine the most effective nebulizer type by comparing the effects of mesh nebulizers (MNs) and compressor nebulizers (CNs) on spirometry tests in pediatric asthma attacks.
Methods: The prospective, double-blind, randomized comparative study was conducted with patients aged 7-15 presenting with asthma attacks.
Volumetric assessment of the soft tissue envelope in unilateral closed ankle fractures using a portable 3D scanner.
J Foot Ankle Surg
January 2025
Department of Orthopedic and Trauma Surgery, University Hospital Düsseldorf Moorenstraße 5, 40255 Düsseldorf, Germany. Electronic address:
Management of ankle fractures necessitating surgery is impacted by soft tissue swelling, often delaying open reduction and internal fixation (ORIF). Subjective evaluations are inconsistent, and traditional measurement methods are often inaccurate or impractical. This prospective observational study included 17 adults with unilateral closed ankle fractures requiring surgical fixation.
View Article and Find Full Text PDFElectrochemical sensor based on tadpole-shaped Au nanostructures supported on TiO: Enhanced detection of nicotine in electronic cigarettes and clinical samples.
Talanta
January 2025
Ampere - Laboratório de Plataformas Eletroquímicas. Departamento de Química, Universidade Federal de Santa Catarina, 880400-900, Florianópolis, SC, Brazil. Electronic address:
Nicotine (NIC) detection is vital for monitoring its presence in various environments, including tobacco products, electronic cigarettes, and clinical samples; NIC's widespread use and health implications necessitate precise and reliable detection methods as it is linked to diseases such as lung cancer and vascular disorders. In this study, we developed and characterized Au tadpole-like nanostructures immobilized onto titanium oxide (TiO) to provide a cost-effective and sensitive NIC detection material. The comprehensive characterization of the composite used transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and X-ray diffraction (XRD), showing the robustness of the synthesis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!