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Understanding Health-Related Discussions on Reddit: Development of a Topic Assignment Method and Exploratory Analysis.
JMIR Form Res
January 2025
Larner College of Medicine, University of Vermont, Burlington, VT, United States.
Background: Social media has become a widely used way for people to share opinions about health care and medical topics. Social media data can be leveraged to understand patient concerns and provide insight into why patients may turn to the internet instead of the health care system for health advice.
Objective: This study aimed to develop a method to investigate Reddit posts discussing health-related conditions.
Technological Adjuncts to Streamline Patient Recruitment, Informed Consent, and Data Management Processes in Clinical Research: Observational Study.
JMIR Form Res
January 2025
Northwestern Medicine, Chicago, IL, United States.
Background: Patient recruitment and data management are laborious, resource-intensive aspects of clinical research that often dictate whether the successful completion of studies is possible. Technological advances present opportunities for streamlining these processes, thus improving completion rates for clinical research studies.
Objective: This paper aims to demonstrate how technological adjuncts can enhance clinical research processes via automation and digital integration.
Urgency Prediction for Medical Laboratory Tests Through Optimal Sparse Decision Tree: Case Study With Echocardiograms.
JMIR AI
January 2025
Department of Information Systems and Business Analytics, Iowa State University, Ames, IA, United States.
Background: In the contemporary realm of health care, laboratory tests stand as cornerstone components, driving the advancement of precision medicine. These tests offer intricate insights into a variety of medical conditions, thereby facilitating diagnosis, prognosis, and treatments. However, the accessibility of certain tests is hindered by factors such as high costs, a shortage of specialized personnel, or geographic disparities, posing obstacles to achieving equitable health care.
View Article and Find Full Text PDFAn ecological-evolutionary perspective on the genomic diversity and habitat preferences of the .
Microb Genom
January 2025
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, USA.
Members of the phylum inhabit a wide range of ecosystems including soils. We analysed the global patterns of distribution and habitat preferences of various lineages across major ecosystems (soil, engineered, host-associated, marine, non-marine saline and alkaline and terrestrial non-soil ecosystems) in 248 559 publicly available metagenomic datasets. Classes , , and were highly ubiquitous and showed a clear preference to soil over non-soil habitats, while classes and showed preferences to non-soil habitats.
View Article and Find Full Text PDFDesign strategies and biomedical applications of organic NIR-IIb fluorophores.
Chem Commun (Camb)
January 2025
Marshall Laboratory of Biomedical Engineering, International Cancer Center, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, China.
The introduction of fluorescence imaging (FLI) in near-infrared II sub-channels (NIR-IIb, 1500-1700 nm) has revolutionized the ability to explore complex patho-physiological settings . Despite the transformative potentials, the development of organic NIR IIb dyes encounters considerable difficulties, and only a limited number of such fluorophores have been developed so far. This review systematically introduces design strategies of organic NIR-IIb fluorophores classified by molecular scaffolds, mainly including cyanine dyes and D-A-D small molecule dyes.
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