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Optical Fresnel zone plate flat lenses made entirely of colored photoresist through an i-line stepper.
Light Sci Appl
January 2025
Institute for Photon Science and Technology, The University of Tokyo, Tokyo, Japan.
Light manipulation and control are essential in various contemporary technologies, and as these technologies evolve, the demand for miniaturized optical components increases. Planar-lens technologies, such as metasurfaces and diffractive optical elements, have gained attention in recent years for their potential to dramatically reduce the thickness of traditional refractive optical systems. However, their fabrication, particularly for visible wavelengths, involves complex and costly processes, such as high-resolution lithography and dry-etching, which has limited their availability.
View Article and Find Full Text PDFComparison of physico-chemical properties of different types of orthopedic acrylic cement.
J Biomater Sci Polym Ed
January 2025
Novel Drug Delivery Systems Laboratory, Faculty of Pharmacy, Medical Sciences/University of Tehran, Tehran, Iran.
Analyzing the chemical composition of different kinds of acrylic cement is necessary to understand their properties and suitability for curing bone defects. Conducting various chemical tests can give valuable insight into the composition, viscosity, and performance characteristics of each kind of cement, Therefore, our study aimed to find safety standards and the effectiveness of these products for medical applications. The polymeric characterization was determined by Nuclear Magnetic Resonance (H-NMR) spectroscopy and Fourier-transform infrared spectroscopy (FTIR).
View Article and Find Full Text PDFThe Effect of Life Activity Levels of Palliative Care Patients on the Caregivers' Perception of Caregivers Burden.
J Palliat Care
January 2025
Florence Nightingale Faculty of Nursing, Istanbul University-Cerrahpaşa, Department of Fundamentals of Nursing, Istanbul, Türkiye.
Studies show the effects of dependent patients' caregivers on the caregiving burden. Knowing the effects of maintenance of movement, especially in life activities, on the factors affecting the caregiving burden is important for the quality of care, ensuring that the caregiver's capacity is preserved. This descriptive and cross-sectional study research was carried out to determine the effect of life activity levels of palliative care patients on the care burden of caregivers.
View Article and Find Full Text PDFKeratoconus in children in Tunisia: Epidemiological, clinical and therapeutic features.
Tunis Med
January 2025
Department of Ophtalmology, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Aim: To report the clinical and therapeutic particularities of pediatric keratoconus (KC).
Methods: Retrospective study focusing on patients aged less than 18 years, presenting with KC and followed in a tertiary reference center in Sfax, Tunisia.
Results: Our study involved 38 eyes of 20 children.
Simulation of Antral Conditions for Estimating Drug Apparent Equilibrium Solubility after a High-Calorie, High-Fat Meal.
Mol Pharm
January 2025
Department of Pharmacy, National and Kapodistrian University of Athens, Zografou 15771, Greece.
The simulation of antral conditions for estimating drug apparent equilibrium solubility after a high-calorie, high-fat meal is challenging. In this study, (1) we measured the apparent equilibrium solubility of two model lipophilic drugs, ketoconazole and danazol, in antral aspirates collected at various time points after a minced high-calorie, high-fat meal and a glass of water 30 min after initiation of meal administration, and we designated one point estimate for ketoconazole and one point estimate for danazol; (2) we evaluated the usefulness of FeSSGF-V2 and FEDGAS pH = 3 in reproducing the two point estimates; (3) we evaluated potential compositions of FeSSGF-V3 that simulate the pH, the buffer capacity toward both less acidic and more acidic values, and the antral lipid and protein contents with easily accessible, commercially available products, and (4) we identified the most useful composition of FeSSGF-V3 for reproducing the two point estimates. For both model drugs, apparent solubility in FeSSGF-V2 and in FEDGAS pH 3 deviated substantially from the corresponding point estimate.
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