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Study on the infection characteristics and pathogenesis of duck circovirus 1 in Cherry Valley meat ducks.
Poult Sci
January 2025
Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian, 271017, China; Shandong Provincial Key Laboratory of Zoonoses, Shandong, Taian, 271017, China. Electronic address:
Duck circovirus (DuCV) infected multiple breeds of ducks and was widespread in duck factories worldwide. Infected ducks exhibited feathering disorder, growth retardation and immunosuppression, which lead to secondary infection with other pathogens easily. But till now, there has been little research on the study of DuCV due to the absence of appropriate cultural measures.
View Article and Find Full Text PDFSingle-cell RNA sequencing reveals intrahepatic signature related to pathobiology of duck hepatitis A virus type 3 (DHAV-3) infection.
Poult Sci
January 2025
College of Animal Science and Technology, Northwest A&F University, Yangling 712100 Shaanxi, PR China. Electronic address:
DHAV-3 is one of the main causative agents of duck viral hepatitis (DVH), an acute and highly lethal infectious disease in duck industry. However, the understanding of the pathogenesis of this virus in ducklings is limited. To dissect the molecular characteristics associated with pathobiology of ducklings to DHAV-3, we applied single-cell RNA-sequencing approach to profile the transcriptome of 1.
View Article and Find Full Text PDFMolecular and phylogenetic analyses of the first complete genome sequence of Duck hepatitis A virus genotype 2 from India.
Gene
March 2025
National Institute of Animal Biotechnology, Hyderabad, Telangana 500032, India; Regional Center for Biotechnology (RCB), Faridabad, Haryana, India. Electronic address:
Duck viral hepatitis (DVH) caused by duck hepatitis A virus (DHAV) is a highly contagious and economically important disease of ducklings worldwide. In many parts of the globe, disease outbreaks are reported in spite of vaccinations, probably due to antigenic diversity among DHAV genotypes. We previously reported the first isolation of DHAV-2 (Genotype-2) from ducklings in Tamil Nadu, India.
View Article and Find Full Text PDFHost-derived Bacillus antagonistic novel duck reovirus infection by regulating gut microbiota-mediated immune responses.
Vet Microbiol
January 2025
College of Veterinary Medicine, Hebei Agricultural University, NO.2596 Lekai South Street, Baoding, Hebei 071000, China; Veterinary Biological Technology Innovation Centre of Hebei Province, Baoding, Hebei 071000, China. Electronic address:
The Novel Duck Reovirus (NDRV) infection poses a significant health risk to ducks, primarily attributed to the absence of efficacious preventive measures. This research aimed to investigate whether the administration of isolated Bacillus could protect antagonistic NDRV infection in a Cherry Valley duck model. Four indigenous Bacillus strains from the feces of healthy ducks demonstrated promising biosafety profiles.
View Article and Find Full Text PDFMatrine relieved DHAV-1-induced hepatocyte excessive interferon and pyroptosis by activating mitophagy.
Poult Sci
January 2025
MOE Joint International Research Laboratory of Animal Health and Food Safety and Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:
Duck hepatitis A virus type 1 (DHAV-1) is a significant pathogen affecting ducklings, capable of causing rapid mortality and adversely impacting the development of the duck industry. Matrine, the primary active ingredient in various Chinese herbal medicines, has demonstrated antiviral and anti-inflammatory properties. Nevertheless, the effects and mechanisms of action of matrine against DHAV-1 infection remain unclear.
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