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Pretreatment attrition after rifampicin-resistant tuberculosis diagnosis with Xpert MTB/RIF or ultra in high TB burden countries: a systematic review and meta-analysis.
BMJ Glob Health
January 2025
Unit of HIV and Tuberculosis, Institute of Tropical Medicine Department of Clinical Sciences, Antwerpen, Belgium.
Introduction: The WHO endorsed the Xpert MTB/RIF (Xpert) technique since 2011 as initial test to diagnose rifampicin-resistant tuberculosis (RR-TB). No systematic review has quantified the proportion of pretreatment attrition in RR-TB patients diagnosed with Xpert in high TB burden countries.Pretreatment attrition for RR-TB represents the gap between patients diagnosed and those who effectively started anti-TB treatment regardless of the reasons (which include pretreatment mortality (death of a diagnosed RR-TB patient before starting adequate treatment) and/or pretreatment loss to follow-up (PTLFU) (drop-out of a diagnosed RR-TB patient before initiation of anti-TB treatment).
View Article and Find Full Text PDFScientific investigation on antibacterial, antioxidant, cytotoxic effects and TLC bioautography of stem bark extracts.
J Complement Integr Med
January 2025
PKFokam Institute of Excellence, Yaoundé, Cameroon.
Objectives: Hochst, belonging to the family, is known for its ethnomedicinal values, particularly in treating various diseases in Africa. This study aimed to investigate the antibacterial, antioxidant, and cytotoxic properties of stem bark extracts, with a specific focus on assessing their bioactive potential and identifying active compounds via TLC bioautography.
Methods: The antimicrobial activity was assessed using the agar well diffusion method against selected clinical strains.
A Cameroon Western Regions high-fat diet (MACAPOS 2) induces visceral obesity in rat.
Heliyon
January 2025
Laboratory of Human Metabolism and Non-Communicable Diseases, Research Centre on Health and Priority Pathologies, (IMPM), P.O. Box. 13033, Yaoundé, Cameroon.
The prevalence of obesity increases yearly in the world. The traditional local diet of the Western Regions of Cameroon was suspected to be the main contributor to the high prevalence of obesity in these Regions. This study aimed to evaluate the effects of a Cameroon-comparable fat diet on visceral obesity in rats.
View Article and Find Full Text PDFImpact of Spodoptera frugiperda (Lepidoptera: Noctuidae), on maize yield in humid tropical zones of Central Africa.
J Econ Entomol
August 2024
Plant Health Department, IITA-Cameroon, P.O. Box. 2008 (Messa), IRAD Main Road, Nkolbisson, Yaoundé, Cameroon.
Fall armyworm, Spodoptera frugiperda Smith, became the most important maize pest in Africa in 2016, with management based on chemical pesticides. High yield losses across the continent were predicted based on farmers' perceptions, but existing agroecological differences were not considered. In the Democratic Republic of Congo, experiments were conducted to assess fall armyworm damage and yield losses in maize farms with and without treatment.
View Article and Find Full Text PDFSuccessful management of an advanced interstitial ectopic pregnancy in a resource-limited setting: a case report.
J Med Case Rep
March 2024
Faculty of Health Sciences, University of Buea, Buea, Cameroon.
Background: Interstitial ectopic pregnancy is an ectopic gestation developing in the uterine part of the fallopian tube. The condition is rare and presents challenges for clinical as well as radiological diagnosis. This case report presents a rare case of interstitial ectopic pregnancy diagnosed intraoperatively.
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