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Cannabis consumption and risk of asthma: a systematic review and meta-analysis.
BMC Pulm Med
January 2025
Global Health and Infectious Diseases Control Institute, Nasarawa State University, Keffi, Nigeria.
Background: Cannabis is the third most widely used psychoactive substance globally, and its consumption has been increasing, particularly with the growing trend of legalization for medicinal and recreational use. Recent studies have raised concerns about the potential impact of cannabis on respiratory health, specifically the risk of asthma, a significant public health concern. This systematic review aimed to consolidate research on the association between cannabis use and the risk of asthma.
View Article and Find Full Text PDFA clinical narrative corpus on nut allergy: annotation schema, guidelines and use case.
Sci Data
January 2025
Computer Science and Engineering Department, Universidad Carlos III de Madrid, Av. Universidad, 30, Leganés, 28911, Madrid, Spain.
This article describes a dataset on nut allergy extracted from Spanish clinical records provided by the Hospital Universitario Fundación de Alcorcón (HUFA) in Madrid, Spain, in collaboration with its Allergology Unit and Information Systems and Technologies Department. There are few publicly available clinical texts in Spanish and having more is essential as a valuable resource to train and test information extraction systems. In total, 828 clinical notes in Spanish were employed and several experts participated in the annotation process by categorizing the annotated entities into medical semantic groups related to allergies.
View Article and Find Full Text PDFThe Efficacy of Superior Laryngeal Nerve Block for Chronic Cough: A Scoping Review.
J Voice
January 2025
Department of Otolaryngology-Head and Neck Surgery, Wake Forest University School of Medicine, Winston-Salem, NC.
Objective: Chronic cough poses diagnostic and treatment challenges due to its often multifactorial nature. Chronic cough associated with laryngeal hypersensitivity is linked to sensory neuropathy of the superior laryngeal nerve and can be complex to manage. Superior laryngeal nerve (SLN) blocks are increasingly being utilized by laryngologists to treat refractory chronic cough with the intent of reducing inflammation and nerve hypersensitivity.
View Article and Find Full Text PDFLeflunomide-induced drug reaction eosinophilia systemic symptoms and haemophagocytic lymphohistiocytosis overlap syndrome with rheumatoid arthritis.
BMJ Case Rep
January 2025
Department of Infectious Diseases, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and haemophagocytic lymphohistiocytosis (HLH) are rare but severe immune-mediated diseases with overlapping clinical manifestations. We present a case of a woman in her late 40s with rheumatoid arthritis who developed DRESS/HLH overlap syndrome after starting hydroxychloroquine and leflunomide therapy. Despite corticosteroid treatment, her condition worsened, necessitating etoposide therapy.
View Article and Find Full Text PDFClinical effectiveness and implementation outcomes of pMDI-to-DPI switch in children between 5 and 12 years of age: a scoping review protocol.
BMJ Open
January 2025
Centre for Behavioural and Implementation Science Interventions, National University of Singapore Yong Loo Lin School of Medicine, Singapore.
Introduction: Inhalers are critical in asthma treatment, and inappropriate inhaler use leads to poor asthma outcomes. In adults and adolescents, dry powder inhalers (DPIs) are safe and effective alternatives to mainstay pressurised metered dose inhalers and could bridge the asthma care gap while also reducing the environmental burden of asthma care. Despite being licensed for use in ages 5 years old and older, the evidence for clinical effectiveness is less clear for patients between ages 5 and 12 years.
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