Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
[Long QT syndrome under cisapride in neonates and infants].
Arch Pediatr
June 1997
Service de cardiologie, hôpital Robert-Debré, Paris, France.
Background: Cisapride is frequently used in the newborn and infant for treatment of gastroesophageal reflux. Twisting-spikes have been reported in adults due to overdosage or therapeutic interaction. We report seven cases of QT prolongation in infants treated with cisapride.
View Article and Find Full Text PDFPathogenesis and treatment of neuroleptic malignant syndrome.
Gen Pharmacol
September 1990
Department of Pharmacology, University of Nebraska College of Medicine, Omaha 68105.
1. Neuroleptic drugs (antipsychotics) produce numerous side effects which include serious extrapyramidal symptoms consisting of akathisia, dystonia, neuroleptic malignant syndrome, parkinsonian reactions such as postural abnormality, tremor, akinesia or bradykinesia, rigidity, and tardive dyskinesia. 2.
View Article and Find Full Text PDFUsing the Adverse Reactions Register to study the effects of age and sex on adverse drug reactions.
Stat Med
February 1988
Department of Medical Statistics, University of Newcastle upon Tyne, Medical School, U.K.
Many countries maintain a register of reports of adverse reactions to drugs. Although reports are made voluntarily by doctors and dentists these registers contain much information that may be useful in pharmaco-epidemiological studies. We show how the epidemiology of adverse drug reactions (ADRs) can be studied using data from such a register, together with estimates of the numbers of prescriptions of the drug, categorized by age and sex of the patient.
View Article and Find Full Text PDFDystonic reactions with metoclopramide: is there a risk population?
Helv Paediatr Acta
June 1987
Pediatric Department, Hôpital Charles Nicolle, Rouen, France.
The authors examine 18 cases of early dystonic syndromes and review all the pediatric cases published previously in order to determine the evolutive and epidemiological characters of these intolerance reactions. These unrecognized manifestations normally occur within the first 24 hours of treatment and disappear within a few hours when the treatment is discontinued. The use of diazepam and trihexyphenidyl accelerates the regression of the disorders.
View Article and Find Full Text PDFIn therapeutic doses paracetamol is a safe analgesic, but in overdosage it can cause severe hepatic necrosis. Following oral administration it is rapidly absorbed from the gastrointestinal tract, its systemic bioavailability being dose-dependent and ranging from 70 to 90%. Its rate of oral absorption is predominantly dependent on the rate of gastric emptying, being delayed by food, propantheline, pethidine and diamorphine and enhanced by metoclopramide.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!