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Non-Melanoma-Associated Dyschromia of the Proximal Nail Fold.
Cureus
December 2016
Department of Dermatology, University of California, San Diego.
Subungual melanoma with pigmentation beneath the nail that extends to involve the proximal nail fold is referred to as Hutchinson's sign. Black or brown subungual discoloration involving the proximal nail fold secondary to other etiologies has been referred to as pseudo-Hutchinson's sign. Three patients with nail discoloration and concurrent dyschromia of the proximal nail fold are described: a female with a chronic subungual hematoma and pseudo-Hutchinson's sign, a male with culture-confirmed (of the nail with green discoloration involving the proximal nail fold, and a male with an acute subungual hematoma with red-purple subungual discoloration affecting the proximal nail fold.
View Article and Find Full Text PDFEditor's perspective: Reentry, pseudo-reentry, and pseudo-pseudo-reentry.
Circ Arrhythm Electrophysiol
June 2014
From the Division of Cardiovascular Diseases, Department of Internal Medicine and Division of Pediatric Cardiology, Department of Pediatrics and Adolescent Medicine, Mayo Clinic, Rochester, MN (S.J.A.); and Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (W.G.S.).
Incessant tachycardia following posteroseptal pathway ablation: a pseudo-r' or pseudo-pseudo-r' wave in V1?
Pacing Clin Electrophysiol
November 2010
Department of Cardiac Electrophysiology, St. Vincent's Hospital, Darlinghurst, Sydney, Australia.
Crystal-storing histiocytosis with renal Fanconi syndrome: pathological and molecular characteristics compared with classical myeloma-associated Fanconi syndrome.
Nephrol Dial Transplant
September 2010
Université de Limoges, Centre National de la Recherche Scientifique (CNRS) UMR 6101, CHU Limoges, France.
Background: Crystal-storing histiocytosis (CSH) is a poorly described complication of monoclonal gammopathy featuring histiocyte lysosomal storage of kappa light chain (kappa LC) crystals. Although CSH is usually associated with systemic manifestations, renal involvement is uncommon.
Methods: To investigate the molecular mechanisms implicated in kappa LC crystallization, we performed immunopathological and molecular studies in three patients with CSH and renal Fanconi syndrome (CSH/FS).
[Epigenetics and pseudohypoparathyroidism].
Pathol Biol (Paris)
October 2010
Laboratoire de Génétique Moléculaire, Département Génétique et Reproduction, CHU de Caen, avenue G.-Clemenceau, 14033 Caen, France.
Parental imprinting and the type of the genetic alteration play a determinant role in the phenotype expression of GNAS locus associated to pseudohypoparathyroidism (PHP). This imprint is tissue-specific, mainly localized in the kidney and the thyroid. Only the maternal allele is expressed at this level.
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