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Respiratory Function Tolerance of Rats with Vaying Degrees of Thoracic Volume Reduction.
Orthop Surg
April 2023
National Center for Trauma Medicine, Trauma Medicine Center, Ministry of Education Key Laboratory of Trauma and Neuroregeneration, Peking University People's Hospital, Beijing, China.
Objective: To compare the effects of respiratory function on different degrees of reduced thoracic volume and evaluate the tolerance of rats with reduced thoracic volume, and to assess the feasibility of thoracic volume as a measure of the severity of rib fractures.
Methods: A total of 24 10-week-old female Sprague-Dawley (SD) rats were randomly divided into four groups (n = 6 in each group) according to the displacement degree of bilateral rib fractures (2, 4, 6, and 8 mm). The respiratory function of the rats（Tidal volume, Inspiration time, Expiration time, Breath rate, Minute volume, Peak inspiration flow) measured via whole-body barometric plethysmography before and after operation for 14 consecutive days.
Effects of extremity trauma on physiological responses to hemorrhage in conscious rats.
J Appl Physiol (1985)
January 2023
US Army Institute of Surgical Research, Joint Base San Antonio-Fort Sam Houston, San Antonio, Texas.
Although physiological responses to hemorrhage are well-studied, hemorrhage is often accompanied by trauma, and it remains unclear how injury affects these responses. This study examined effects of extremity trauma on cardiorespiratory responses and survival to moderate (37%; H-37) or severe (50%; H-50) hemorrhage in rats. Transmitter and carotid catheter implantation and extremity trauma (fibular fracture and muscle injury) were conducted 2 wk, 24 h, and 90 min, respectively, before conscious hemorrhage.
View Article and Find Full Text PDFEffects of ketamine analgesia on cardiorespiratory responses and survival to trauma and hemorrhage in rats.
J Appl Physiol (1985)
May 2021
United States Army Institute of Surgical Research, JBSA Fort Sam Houston, Texas.
Ketamine is the recommended analgesic on the battlefield for soldiers with hemorrhage, despite a lack of supportive evidence from laboratory or clinical studies. Hence, this study determined the effects of ketamine analgesia on cardiorespiratory responses and survival to moderate (37% blood volume; = 8/group) or severe hemorrhage (50% blood volume; = 10/group) after trauma in rats. We used a conscious hemorrhage model with extremity trauma (fibular fracture + soft tissue injury) while measuring mean arterial pressure (MAP), heart rate (HR), and body temperature (T) by telemetry, and respiration rate (RR), minute volume (MV), and tidal volume (TV) via whole body plethysmography.
View Article and Find Full Text PDFData-driven assessment of cardiovascular ageing through multisite photoplethysmography and electrocardiography.
Med Eng Phys
November 2019
Department of Neuroscience and Imaging, Institute for Advanced Biomedical Technologies, University G. D'Annunzio of Chieti-Pescara, Via Luigi Polacchi 13, Chieti 66100, Italy.
The cardiovascular system is designed to distribute a steady flow through its elastic properties. With ageing, fatigue and fracture of elastin lamellae cause a loss of elasticity defined arterial stiffness. Arterial stiffness causes changes of the pulse wave propagation through the arterial tree, which volumetric counterpart can be assessed non-invasively through photoplethysmography (PPG).
View Article and Find Full Text PDFTherapeutic Effect of C. Y. Cheng et T. M. Ai in Ovalbumin-Induced Murine Model of Asthma.
Int J Mol Sci
April 2019
Herbal Medicine Resources Research Center, Korea Institute of Oriental Medicine, Geonjae-ro 177, Naju-si, Jeollanam-do 58245, Korea.
C. Y. Cheng et T.
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