Our experience is outlined with 138 cases of bilharzial bladder cancer treated by radical cystectomy and followed for 5 years. The operative mortality was 13.7%. The 5-year survival rate was 32.6%. Analysis of survival figures revealed that the tumour grade was the most important prognostic factor. Most treatment failures were due to local recurrence which developed early after treatment. It was concluded that improvement in survival might be obtained by some form of pre-operative irradiation augmented by the use of a hypoxic cell sensitiser.

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http://dx.doi.org/10.1111/j.1464-410x.1979.tb03597.xDOI Listing

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Article Synopsis
  • * A case is reported involving a 64-year-old man with mixed large and small cell neuroendocrine tumors of the bladder, diagnosed after a radical cystectomy and supported by specific immunohistochemical staining.
  • * The case is significant because it is the first documented occurrence of mixed neuroendocrine carcinoma connected to bilharzial cystitis, suggesting the need for more research on their relationship and similar patterns in other organs.
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