Cholesterol is biosynthesized from squalene in the presence of tritiated water. Chemical degradation reveals that a considerable percentage of the total radioactivity is present at C-15. This result confirms the previous observations on the involvement of a C-15 hydrogen atom in cholesterol biosynthesis.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184967 | PMC |
| http://dx.doi.org/10.1042/bj1140801 | DOI Listing |
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