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Risk Factors and Prognosis for Metastatic Cutaneous Squamous Cell Carcinoma: A Cohort Study.
Acta Derm Venereol
September 2020
Department of Dermatology, University of Turku and Turku University Hospital, FIN-20520 Turku, Finland.
Cutaneous squamous cell carcinoma (cSCC) has metastatic potential. The aims of this study were to identify the risk factors for metastasis of primary cSCC and for poor prognosis in metastatic cSCC. Retrospective primary tumour cohorts of metastatic cSCCs (n = 85) and non-metastatic cSCCs (n = 218) were analysed.
View Article and Find Full Text PDFImpact of the halitosis on QoL in overweight and obese patients: Based on six years of experience in two centers in sulaimani governorate, Kurdistan Region/Iraq, and case series study.
Ann Med Surg (Lond)
July 2019
Kurdistan Board Trainee in General Surgery, Iraq.
Background/objectives: The patients who are overweight and obese, are under stress of excess body weight, embarrassed, one may imagine the impact of halitosis on this group of patients, this is an attempt to evaluate this extra impact, and which aspect of quality of life will be affect in the overweight and obese.
Subjects/methods: A prospective case series study including 885 overweight or obese patients, they were consulting for advice, diet and or drugs and various bariatric operations. A group of normal weight patients with halitosis, matched in age group and gender were enrolled as a control group for comparison.
Study of efficacy and safety of a new local cream ('healer') in the treatment of chronic anal fissure: a prospective, randomized, single-blind, comparative study.
Arq Gastroenterol
March 2010
Green Clinic, Alexandria, Egypt.
Objectives: To determine the efficacy and safety of 'healer' cream as monotherapy in the treatment of acute and chronic anal fissure.
Study Design: A prospective, randomized, single blinded, comparative trial.
Methods: Sixty patients suffering from anal fissure were included in the study.
Treatment of portal hypertension with NCX-1000, a liver-specific NO donor. A review of its current status.
Cardiovasc Drug Rev
October 2004
Dipartimento di Medicina Clinica e Sperimentale, Clinica di Gastroenterologia ed Epatologia, Universita degli Studi di Perugia, Via E dal Pozzo, 06122, Perugia, Italy.
Portal hypertension, a life threatening complication of liver cirrhosis, results from increased intrahepatic resistance and increased portal blood inflow through a hyperdynamic splanchnic system. The increased intrahepatic vascular tone is the result of an enhanced activity of endogenous vasoconstrictors and a deficiency of nitric oxide (NO) release by sinusoidal endothelial cells. These pathophysiological events provide the rational basis for using NO-based therapies for the treatment of portal hypertension.
View Article and Find Full Text PDFAnal fissure: new concepts in pathogenesis and treatment.
Scand J Gastroenterol Suppl
January 1997
Dept. of Surgery, University Hospital Dijkzigt, Rotterdam, The Netherlands.
The posterior commissure of the anal canal is less well perfused than the other segments of the anoderm. There is growing evidence that the increased activity of the internal anal sphincter, which is found in almost all patients with a chronic anal fissure, further decreases the anodermal blood supply, especially at the posterior midline. Reduction of anal pressure, either by anal dilatation or by lateral internal sphincterotomy, is the most important step in the treatment of chronic anal fissure.
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