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Gaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused research.
Alzheimers Dement
December 2024
Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA.
Frontotemporal dementia (FTD) is one of the leading causes of young-onset dementia before age 65, typically manifesting as abnormal behavior (in behavioral variant FTD) or language impairment (in primary progressive aphasia). Although FTD affects all populations across the globe, knowledge regarding the pathophysiology and genetics derives primarily from studies conducted in North America and Western Europe. Globally, biomedical research for FTD is hindered by variable access to diagnosis, discussed in this group's earlier article, and by reduced access to expertise, funding, and infrastructure.
View Article and Find Full Text PDFBritish Society of Echocardiography guideline for the transthoracic echocardiographic assessment of cardiac amyloidosis.
Echo Res Pract
August 2023
Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Edgbaston, Birmingham, B15 2TH, UK.
These guidelines form an update of the BSE guideline protocol for the assessment of restrictive cardiomyopathy (Knight et al. in Echo Res Prac, 2013). Since the original recommendations were conceived in 2013, there has been an exponential rise in the diagnosis of cardiac amyloidosis fuelled by increased clinician awareness, improvements in cardiovascular imaging as well as the availability of new and effective disease modifying therapies.
View Article and Find Full Text PDFSixty years of learning and teaching physiology.
Adv Physiol Educ
December 2023
Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States.
This is a memoir of my experiences in learning and teaching Physiology. It begins in 1962 when I entered the University of Washington as a medical student and began research in a physiology laboratory, which led to a Ph.D.
View Article and Find Full Text PDFGaps in clinical research in frontotemporal dementia: A call for diversity and disparities-focused research.
Alzheimers Dement
December 2023
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Article Synopsis
- Frontotemporal dementia (FTD) is a major cause of dementia in people under 65, showing symptoms like unusual behavior or language difficulties depending on the variant.
- The symptoms and presentation of FTD can differ significantly across cultures and socioeconomic backgrounds, but most current research is based on Western populations.
- The paper discusses how global diversity influences FTD's diagnosis and treatment, and suggests changes to improve the understanding and management of FTD worldwide.
No place in France for repetitive transcranial magnetic stimulation in the therapeutic armamentarium of treatment-resistant depression?
Brain Stimul
June 2023
Pôle Hospitalo-Universitaire de Psychiatrie Adulte, Centre Hospitalier Guillaume Régnier, Rennes, France; Centre d'Investigation Clinique 1414, INSERM, Neuropsychiatrie du développement et du Comportement, CHU Rennes / Université de Rennes, Rennes, France.
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