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Phage-Antibiotic Combination Therapy against Recurrent Septicaemia in a Patient with an Arterial Stent.
Antibiotics (Basel)
September 2024
Human Microbiome Research Program, Research Programs Unit and Medicum, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Intravascular stent infections are often associated with high risks of morbidity and mortality. We report here a case of a patient with an arterial stent and recurrent septicaemias successfully treated with phage-meropenem combination therapy. A 75-year-old female with arteriosclerosis and comorbidities went through a femoropopliteal bypass with prosthesis in the right inguinal area.
View Article and Find Full Text PDFCauses, risk factors, and complications of accidental intra-arterial administration of medications in a children's hospital: a case series.
JA Clin Rep
September 2024
Tokyo Metropolitan Children's Medical Center, 2-8-29 Musashidai, Fuchu-Shi, Tokyo, 184-8561, Japan.
Background: Accidental intra-arterial administration of a medication can lead to serious iatrogenic harm. Most studies have discussed single cases of accidental intra-arterial administration of a medication, but only a few have described multiple cases occurring in a single, pediatric hospital setting.
Methods: The subjects were pediatric patients with an accidental intra-arterial administration of a medication.
Effectiveness and Safety of Intra-arterial Imipenem/Cilastatin Sodium Infusion for Patients with Hand Osteoarthritis-Related Interphalangeal Joint Pain.
J Vasc Interv Radiol
September 2023
Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; School of Medicine, Chung Shan Medical University, Taichung, Taiwan; Department of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, Taiwan. Electronic address:
Article Synopsis
- * A total of 58 patients were evaluated, with significant improvements in pain and function measured through various scales over 18 months, showing a marked decrease in pain scores.
- * No severe side effects were reported, and the treatment emerged as a promising option for patients not responding to traditional therapies for joint osteoarthritis.
Contrast-Induced Encephalopathy: A Clinical Conundrum.
Cureus
November 2022
Ear, Nose, and Throat (ENT), Government Medical College and Hospital, Surat, IND.
Contrast-induced encephalopathy (CIE) is a rare but well-known complication of mostly intra-arterial contrast administration and presents with a variety of neurological deficits due to disruption of the blood-brain barrier. We present a case of CIE after administration of intravenous contrast for computed tomography pulmonary angiogram (CTPE). A woman in her mid-70s with history of chronic obstructive pulmonary disease (COPD) presented with progressively worsening shortness of breath.
View Article and Find Full Text PDFTemsirolimus Adventitial Delivery to Improve ANGiographic Outcomes Below the Knee.
J Endovasc Ther
August 2024
North American Science Associates, New York, NY, USA.
Background: Current endovascular treatments of below the knee (BTK) popliteal or tibial/peroneal arteries including investigational drug-coated balloons have limited long-term efficacy.
Objectives: This Phase 2 trial assessed the feasibility of adventitial deposition of temsirolimus to reduce neointimal hyperplasia and clinically relevant target lesion failure (CR-TLF) 6 months after BTK arterial revascularization.
Methods: This prospective, multicenter, double-blinded, comparative, dose-escalation trial enrolled 61 patients with Rutherford 3 to 5 symptoms undergoing endovascular revascularization of ≥1 angiographically significant BTK lesions.
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