Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Modulating the antibacterial effect of the existing antibiotics along with repurposing drug metformin.
Arch Microbiol
March 2024
University of Rajshahi, Rajshahi, 6205, Bangladesh.
Owing to the extensive prevalence of resistant bacteria to numerous antibiotic classes, antimicrobial resistance (AMR) poses a well-known hazard to world health. As an alternate approach in the field of antimicrobial drug discovery, repurposing the available medications which are also called antibiotic resistance breakers has been pursued for the treatment of infections with antimicrobial resistance pathogens. In this study, we used Haloperidol, Metformin and Hydroxychloroquine as repurposing drugs in in vitro (Antibacterial Antibiotic Sensitivity Test and Minimum Inhibitory Concentration-MIC) and in vivo (Shigellosis in Swiss albino mice) tests in combination with traditional antibiotics (Oxytetracycline, Erythromycin, Doxycycline, Gentamicin, Ampicillin, Chloramphenicol, and Penicillin) against a group of AMR resistance bacteria (Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Shigella boydii).
View Article and Find Full Text PDFAnti-virulence and bactericidal activities of Stattic against .
Appl Environ Microbiol
December 2023
School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Sun Yat-sen University, Shenzhen, China.
is a major human enteric pathogen that causes bacillary dysentery. The increasing spread of drug-resistant strains has caused an emergent need for the development of new antimicrobial agents against this pathogenic bacterium. In this study, we demonstrate that Stattic employs two antibacterial mechanisms against .
View Article and Find Full Text PDFA Review on the Antibiotic Resistance of Strains in Iran.
Infect Disord Drug Targets
January 2024
Faculty of Paramedical Sciences, Mazandaran University of Medical Sciences, Sari, Iran.
Shigella infection is commonly related to diarrhea and has been a noteworthy source of morbidity and mortality worldwide. There is a wide range of symptoms associated with these contagious microorganisms, from watery diarrhea to fulminant dysentery manifesting with recurrent bloody stools, fever, and prostration. While the mortality rate from Shigellosis has decreased significantly during the past three decades, it remains a principal cause of death in the world.
View Article and Find Full Text PDFPrevalence and Antimicrobial-Resistant Features of Species in East Africa from 2015-2022: A Systematic Review and Meta-Analysis.
Interdiscip Perspect Infect Dis
September 2023
Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Background: Shigellosis is the most common cause of epidemic dysentery found worldwide, particularly in developing countries, where it causes infant diarrhea and mortality. The prevalence of species resistant to commonly used antimicrobial drugs has steadily increased. The purpose of this review is to describe the prevalence and antimicrobial resistance (AMR) characteristics of species in East Africa between 2015 and 2022.
View Article and Find Full Text PDFIdentification and antibiotic pattern analysis of bacillary dysentery causing bacteria isolated from stool samples of infected patients.
Biologia (Bratisl)
December 2022
Department of Applied Nutrition and Food Technology, Faculty of Biological Sciences, Islamic University, 7003 Kushtia, Bangladesh.
Unlabelled: Bacillary dysentery is a type of dysentery and a severe form of shigellosis. This dysentery is usually restricted to infection, but and enteroinvasive strains are also known as this infection's causative agents. The emergence of drug-resistant, bacillary dysentery-causing pathogens is a global burden, especially for developing countries with poor hygienic environments.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!