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Successful Treatment of Large Left Ventricular Thrombosis During Extracorporeal Membrane Oxygenation (ECMO): A Case Report and Review of the Literature.
Clin Case Rep
January 2025
Emergency Intensive Care Unit Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu Sichuan China.
We report a rare complication of left ventricular giant thrombus in a patient with fulminant myocarditis after venoarterial extracorporeal membrane oxygenation therapy. This case report offers simple anticoagulant treatment experiences to eliminate significant LV thrombosis in patient undergoing extracorporeal membrane oxygenation, so that patients do not need surgery.
View Article and Find Full Text PDFCardiovascular and thromboembolic outcomes with immune checkpoint inhibitors in gastroesophageal cancer: a propensity score-matched cohort study.
Gastric Cancer
January 2025
Department of Medicine, Mount Auburn Hospital, Harvard Medical School, 330 Mt Auburn St, Cambridge, MA, MA 02138, USA.
Background: Immune checkpoint inhibitors (ICIs) have been associated with an increased risk of cardiovascular and thromboembolic events. However, the incidence of cardiovascular and thromboembolic events associated with ICIs in gastroesophageal cancers is unknown.
Methods: We performed a propensity score-matched cohort study using the TriNetX Analytics Network database, which comprises de-identified data from over 130 participating healthcare institutions.
Cardiotoxic Effects Following CAR-T Cell Therapy: A Literature Review.
Curr Oncol Rep
January 2025
Department of Radiology, Albert Einstein College of Medicine and the Montefiore Medical Center, 111 East 210Th Street, Bronx, NY, 10461, USA.
Purpose Of Review: This paper reviewed the current literature on incidence, clinical manifestations, and risk factors of Chimeric Antigen Receptor T-cell (CAR-T) cardiotoxicity.
Recent Findings: CAR-T therapy has emerged as a groundbreaking treatment for hematological malignancies since FDA approval in 2017. CAR-T therapy is however associated with a few side effects, among which cardiotoxicity is of significant concern.
Therapeutic effects of platelet-derived extracellular vesicles on viral myocarditis correlate with biomolecular content.
Front Immunol
January 2025
Department of Cardiovascular Medicine, Mayo Clinic, Jacksonville, FL, United States.
Introduction: Extracellular vesicles (EVs) can potently inhibit inflammation yet there is a lack of understanding about the impact of donor characteristics on the efficacy of EVs. The goal of this study was to determine whether the sex and age of donor platelet-derived EVs (PEV) affected their ability to inhibit viral myocarditis.
Methods: PEV, isolated from men and women of all ages, was compared to PEV obtained from women under 50 years of age, which we termed premenopausal PEV (pmPEV).
Syphilitic bi-valvular endocarditis and myocarditis: modern tools applied to long-forgotten complications of a re-emerging disease.
Lancet Infect Dis
January 2025
Department of Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada.
The incidence of syphilis has increased steadily over the past 25 years. Undiagnosed cases have presumably increased in the same proportions, and rare complications are at particularly high risk of being unrecognised. A previously healthy 60-year-old man presented with rapidly progressive heart failure and severe aortic and mitral valve insufficiency, with direct valvular destruction and preservation of the aortic valve annulus and aortic root.
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