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Near-Infrared Fluorescent Probe for Simultaneously Imaging Ferrous Ions and Viscosity in a Mouse Model of Hepatocellular Carcinoma.
Anal Chem
January 2025
College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan 430079, China.
Abnormal ferrous ion (Fe) levels lead to an increase in reactive oxygen species (ROS) in cells, disrupting intracellular viscosity and the occurrence of hepatocellular carcinoma (HCC). Simultaneously visualizing Fe and intracellular viscosity is essential for understanding the detailed pathophysiological processes of HCC. Herein, we report the first dual-responsive probe, , capable of simultaneously monitoring Fe and viscosity.
View Article and Find Full Text PDFCorrigendum to "Patient characteristics in relation to opioid exposure in a chronic non-cancer pain population".
Scand J Pain
January 2025
Department of Clinical Sciences Malmö, Center for Primary Health Care Research, Lund University, Jan Waldenströms Gata 35, 202 13 Malmö, Sweden.
Rh(III)-Catalyzed [4 + 2] Annulation and Dehydrogenative Annulation of -Chloroimines with Maleimides.
J Org Chem
January 2025
Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210023, China.
We herein report a Rh(III)-catalyzed C-H bond coupling of -chloroimines with maleimides, in which the [4 + 2] annulation and dehydrogenative annulation processes can be selectively achieved by simply adjusting the reaction conditions. This protocol is compatible with various functional groups, shows exquisite selectivity, and presents a concise synthetic procedure to respective products in moderate to good yields. With all these merits, this strategy may be applicable in the construction of related azaheterocyclic skeletons.
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