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Impact of pharmacist-led interventions in a multidisciplinary consultation meeting for bone and joint infection.
Infect Dis Now
October 2024
Education - Ethic - Health, EA7505, Tours University, Tours, France.
Introduction: Management of bone and joint infections (BJI) requires prolonged and high-dose antibiotic therapy to achieve target concentrations in bone tissue. However, these therapies often lead to adverse effects in patients who are frequently fragile, with multiple comorbidities and associated medications. The decision to treat these complex cases is made during a multidisciplinary team meeting at the reference centre for complex osteoarticular infections (CRIOAC).
View Article and Find Full Text PDFOsteoarticular tuberculosis of the ankle, a rare localization: a case report.
Access Microbiol
October 2023
Department of Bacteriology, Mohammed V Military Teaching Hospital/Faculty of Medicine and Pharmacy (University Mohammed V), Rabat, Morocco.
Tuberculosis poses a considerable public health problem in countries where the disease is endemic. Osteoarticular tuberculosis represents 3-5 % of all tuberculosis cases and 10-15 % of extra-pulmonary tuberculosis cases. Involvement of the foot and ankle is rarer.
View Article and Find Full Text PDFfoodborne illness outbreak in the elderly.
Front Microbiol
July 2023
Bordeaux Institute of Oncology, BRIC U1312, INSERM, Université de Bordeaux, CHU de Bordeaux, Bordeaux, France.
In June 2021, a cluster of seven cases of infections occurred in a rehabilitation center and caused significant morbidity in elderly patients including five with bacteremia and two with osteoarticular medical device infections. The genetic identity identified by whole genome sequencing of the different strains confirms a common source. This foodborne illness outbreak may have resulted from the consumption of unpasteurized dairy products, such as a cow's raw milk cheese resulting from a farm-to-fork strategy.
View Article and Find Full Text PDFClinical Features and Outcome of Multidrug-Resistant Osteoarticular Tuberculosis: A 12-Year Case Series from France.
Microorganisms
June 2022
Cimi-Paris, INSERM, U1135, Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Université, 75013 Paris, France.
Article Synopsis
- - The study investigates the diagnosis and treatment outcomes of multidrug-resistant osteoarticular tuberculosis (MDR-OATB) in France, based on a review of 23 cases from 2007 to 2018.
- - Most affected patients were young males, with the spine being the most common site of infection; a significant portion had prior tuberculosis treatments.
- - Despite a high treatment success rate (91%) achieved with a mean regimen of four drugs over approximately 20 months, the ideal treatment protocol for MDR-OATB, including drug combinations and surgical options, is still not established.
Retrospective Multicentric Study on Campylobacter spp. Bacteremia in France: The Campylobacteremia Study.
Clin Infect Dis
September 2022
CHU de Bordeaux, Infectious and Tropical Diseases Department, Bordeaux, France.
Background: Campylobacter spp. bacteremia is a severe infection. A nationwide 5-year retrospective study was conducted to characterize its clinical features and prognostic factors.
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