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Evaluating Xanthomonas oryzae pv. oryzae (Xoo) infection dynamics in rice for distribution routes and environmental reservoirs by molecular approaches.
Sci Rep
January 2025
Department of Biology, Faculty of Science, Naresuan University, Phitsanulok, Thailand.
Xanthomonas oryzae pv. oryzae (Xoo) is a bacterial pathogen responsible for bacterial leaf blight (BLB) in rice, which can result in significant yield losses of up to 70%. A study evaluated the spread of Xoo in rice fields using environmental samples and employed colorimetric loop-mediated amplification (cLAMP) and PCR for detection.
View Article and Find Full Text PDFThe role of ribosomal protein networks in ribosome dynamics.
Nucleic Acids Res
January 2025
Institut de Mathématiques de Jussieu - Paris Rive Gauche (IMJ-PRG), UMR 7586, CNRS, Université Paris Diderot, 8, Pace Aurélie Nemours, 75013 Paris, France.
Accurate protein synthesis requires ribosomes to integrate signals from distant functional sites and execute complex dynamics. Despite advances in understanding ribosome structure and function, two key questions remain: how information is transmitted between these distant sites, and how ribosomal movements are synchronized? We recently highlighted the existence of ribosomal protein networks, likely evolved to participate in ribosome signaling. Here, we investigate the relationship between ribosomal protein networks and ribosome dynamics.
View Article and Find Full Text PDFH-NS represses fliD transcription for lateral flagellar filament cap in Vibrio parahaemolyticus.
Arch Microbiol
January 2025
Department of Critical Care Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, PR China.
Vibrio parahaemolyticus propels itself through liquids using a polar flagellum and efficiently swarms across surfaces or viscous environments with the aid of lateral flagella. H-NS plays a negative role in the swarming motility of V. parahaemolyticus by directly repressing the transcription of the lateral flagellin gene lafA.
View Article and Find Full Text PDFOccurrence analysis of alpha-mangostin from different organs of L.
Nat Prod Res
January 2025
Faculty of Chemical and Process Engineering Technology, University Malaysia Pahang Al-Sultan Abdullah, Lebuhraya Persiaran Tun Khalil Yaakob, Gambang, Kuantan, Pahang, Malaysia.
Alpha-mangostin (AM) is a naturally occurring xanthone with remarkable pharmacological properties, including anti-inflammatory, anti-bacterial, and antioxidant effects. The compound is commonly extracted from the pericarps of L. fruits, but its seasonal availability is limited.
View Article and Find Full Text PDFPopulation-level amplification of gene regulation by programmable gene transfer.
Nat Chem Biol
January 2025
Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Engineering cells to sense and respond to environmental cues often focuses on maximizing gene regulation at the single-cell level. Inspired by population-level control mechanisms like the immune response, we demonstrate dynamic control and amplification of gene regulation in bacterial populations using programmable plasmid-mediated gene transfer. By regulating plasmid loss rate, transfer rate and fitness effects via Cas9 endonuclease, F conjugation machinery and antibiotic selection, we modulate the fraction of plasmid-carrying cells, serving as an amplification factor for single-cell-level regulation.
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