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A strain of pathogenic Staphylococcus aureus, grown under special conditions, accumulates extracellular metabolites about the bacterial cells. This phenomenon may simulate, but is differentiable from, the capsulation of, for instance, the mucoid "Smith" strain. The special nutrient requirements, namely lactose, mannitol, vitamin, and gelatin containing medium, promote the production and accumulation about the cells of, in particular, soluble coagulase.
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