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Histopathology of spontaneous lesions in FVB/N mice.
J Toxicol Pathol
January 2025
Safety and Bioscience Research Department, Translational Research Division, Chugai Pharmaceutical Co., Ltd. 216 Totsuka-cho, Totsuka-ku, Yokohama, Kanagawa 244-8602, Japan.
The FVB/N mouse strain is widely used in transgenic studies and as a model for autoimmune diseases. Although spontaneous lesions have been reported in aged FVB/N mice, information regarding younger FVB/N mice is lacking. This study aimed to investigate the spontaneous lesions in young FVB/N mice.
View Article and Find Full Text PDFAnterior Uveitis and Uveal Depigmentation in a Dog With Vitiligo.
Case Rep Vet Med
January 2025
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
The objective of this study is to describe the clinical and histologic features of a dog that developed anterior uveitis and uveal depigmentation in association with vitiligo. A 3-year-old, female-spayed, Bernese Mountain Dog with a history of bilateral idiopathic anterior uveitis developed iris depigmentation, leukotrichia, and skin depigmentation. The initial diagnostic evaluation for uveitis was unremarkable, including general bloodwork, urinalysis, infectious disease testing, thoracic radiographs, and abdominal ultrasound.
View Article and Find Full Text PDFComparative evaluation of funduscopy, PCR and serology in the diagnosis of ocular toxoplasmosis at ECWA Eye Hospital, Kano.
BMJ Open Ophthalmol
January 2025
Federal College of Education (Technical), Bichi, Kano State, Nigeria.
Objective: Ocular toxoplasmosis, caused by , is a significant cause of posterior uveitis and vision impairment globally. Accurate diagnosis is essential to prevent retinal damage and optimise treatment. This study aimed to compare three diagnostic methods funduscopy, serology (ELISA), and PCR in detecting ocular toxoplasmosis in patients at ECWA Eye Hospital, Kano, Nigeria.
View Article and Find Full Text PDFVestibular Function in Patients With Vestibular Neuritis Experiencing Prodromal Dizziness.
Clin Otolaryngol
January 2025
Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Introduction: It is unknown whether prodromal dizziness (PD) before an attack of vestibular neuritis (VN) has an association with peripheral vestibular lesions. The purpose of this study was to investigate whether the severity of vestibular dysfunction has an association with the presence of PD.
Methods: We reviewed the medical records of 88 consecutive unilateral VN patients with unilateral canal paresis in caloric testing.
Ocular Hypertropia Mimicking Inferior Rectus Palsy as an Atypical Presentation of Parameningeal Rhabdomyosarcoma in a Child.
Int Med Case Rep J
January 2025
Department of Pediatric Ophthalmology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Introduction: Rhabdomyosarcoma (RMS) originates from undifferentiated mesenchymal cells that give rise to striated muscles. The symptoms of para-meningeal RMS often resemble those of allergic rhinosinusitis, including nasal congestion, mucus discharge, headache, and occasional nosebleeds. We report a child with atypical clinical presentation of ocular hypertropia secondary to para-meningeal RMS.
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