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Low-Grade Endometrial Stromal Sarcoma: A Case Report of a Rare Uterine Malignancy Mimicking Degenerative Uterine Leiomyoma in a Nulliparous Woman.
Diagnostics (Basel)
December 2024
Department of Radiology, Jeonbuk National University Medical School and Hospital, 20 Geonji-ro, Deokjin-gu, Jeonju 54907, Jeonbuk, Republic of Korea.
Low-grade endometrial stromal sarcoma (LGESS) is a rare uterine malignancy that causes non-specific symptoms which presents more typically in younger women compared to other uterine sarcomas. Preoperative diagnosis of myometrial LGESS is challenging, as it is frequently mistaken for a benign uterine mass, such as a degenerating leiomyoma. Despite its rarity, the imaging findings of LGESS are highly variable, complicating the diagnostic process.
View Article and Find Full Text PDFPredictive value of abnormal expression of MPHOSPH9 in reintervention after high intensity focused ultrasound treatment of uterine fibroids.
J Obstet Gynaecol Res
January 2025
Department of Radiology, Ya'an People's Hospital, Ya'an, China.
Aims: Aberrantly expressed MPHOSPH9 has been reported to be associated with poor prognosis in many diseases. Previous study indicates that MPHOSPH9 is abnormally expressed in patients with uterine fibroids (UFs). This study focused on the possible prognostic value of MPHOSPH9 in UFs patients after high intensity focused ultrasound (HIFU) treatment.
View Article and Find Full Text PDFEpidemiological features of uterine fibroid-associated imaging changes in Chinese women of reproductive age: a retrospective study.
BMJ Open
January 2025
School of Public Health, Chongqing Medical University, Chongqing, China
Objectives: To investigate uterine fibroid (UF)-associated imaging changes, and their prevalence, incidence and potential risk factors in the Chinese population.
Design: This was a retrospective observational study using health examination data.
Setting: A physical examination centre in Nanchong, China, between October 2017 and December 2020.
Validation of biomarkers and clinical scores for the detection of uterine leiomyosarcoma: a case-control study with an update of pLMS.
BMC Cancer
January 2025
Department of Obstetrics and Gynecology, University Medicine Greifswald, Sauerbruchstr., Greifswald, 17475, Germany.
Background: The diagnosis of rare uterine leiomyosarcoma (uLMS) remains a challenge given the high incidence rates of benign uterine tumors such as leiomyoma (LM). In the last decade, several clinical scores and blood serum markers have been proposed. The aim of this study is to validate and update the pLMS clinical scoring system, evaluating the accuracy of the scoring system by Zhang et al.
View Article and Find Full Text PDFNomogram for predicting the efficacy of high-intensity focused ultrasound ablation for uterine fibroids based on oxytocin experimentation and ultrasonographic features: a retrospective single-center study.
Int J Hyperthermia
December 2025
State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical Unibersity, Chongqing, China.
Article Synopsis
- Developed a nomogram to predict the effectiveness of high-intensity focused ultrasound (HIFU) for treating uterine fibroids by analyzing oxytocin levels and sonographic features of fibroids.
- Conducted a retrospective study of 60 patients, utilizing logistic regression to identify key predictive factors like myoma type, blood flow, and oxytocin classification, resulting in a model assessed using R language.
- The model demonstrated strong predictive ability with an area under the curve of 0.887 and good calibration, suggesting it can effectively guide clinicians in selecting appropriate patients for HIFU treatment.
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