As a tumour-producing agent, Shope's rabbit fibroma virus (a member of the myxoma-fibroma subgroup of the poxviruses) is endowed with potentialities which differ from those of vaccinia virus. This work attemps to find, by the technique of the one-step growth curve in suspended cells, if the virus replication scheme is similar to other poxviruses. Fibroma virus seems to multiply rather slowly and to a limited level, but the pattern is characteristic of the poxviruses: eclipse phase, exponential multiplication, reduced release of virus in the medium are the main features.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2554254 | PMC |
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