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Selenocysteine-Activatable Near-Infrared Fluorescent Probe for Screening of Anti-inflammatory Components in Herbs.
Anal Chem
January 2025
Pukou Hospital of Chinese Medicine Affiliated to China Pharmaceutical University, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
Inflammation, a central process in numerous diseases, plays a crucial role in hepatic disorders, arthritis, cardiac conditions, and neurodegenerative ailments. Given the lack of effective anti-inflammatory drugs, it is imperative to assess inflammation severity and explore novel therapeutics. Selenocysteine (Sec), a key mediator of selenium's biological function, is closely involved in anti-inflammatory responses.
View Article and Find Full Text PDFCharacterizing the In Utero Phenome of the Chiari II Malformation-A Network Medicine Approach, Using Fetal MRI.
Prenat Diagn
January 2025
Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Objective: To apply a network medicine-based approach to analyze the phenome of the prenatal fetal MRI and biometric findings in the Chiari II malformation (CM II) to detect specific patterns and co-occurrences.
Method: A single-center retrospective review of fetal MRI scans obtained in fetuses with CM II was performed. Co-occurrence analysis was utilized to generate a phenotypic comorbidity matrix and visualized by Gephi software.
Near real-time change detection tool for photogrammetric flood preparedness.
Environ Monit Assess
January 2025
Technische Hochschule Nürnberg Georg Simon Ohm, Institute of Hydraulic Engineering and Water Resources Management, Nuremberg, Germany.
Through the mobilization of movable objects due to the extreme hydraulic conditions during a flood event, blockages, damage to infrastructure, and endangerment of human lives can occur. To identify potential hazards from aerial imagery and take appropriate precautions, a change detection tool (CDT) was developed and tested using a study area along the Aisch River in Germany. The focus of the CDT development was on near real-time analysis of point cloud data generated by structure from motion from aerial images of temporally separated surveys, enabling rapid and targeted implementation of measures.
View Article and Find Full Text PDFUsing transformer-based models and social media posts for heat stroke detection.
Sci Rep
January 2025
Chubu Institute for Advanced Studies, Chubu University, Kasugai, Aichi, Japan.
Event-based surveillance is crucial for the early detection and rapid response to potential public health risks. In recent years, social networking services (SNS) have been recognized for their potential role in this domain. Previous studies have demonstrated the capacity of SNS posts for the early detection of health crises and affected individuals, including those related to infectious diseases.
View Article and Find Full Text PDFPreretinal abnormal tissue before and after pars plana vitrectomy in macula-on rhegmatogenous retinal detachment: a multimodal imaging study.
Br J Ophthalmol
January 2025
Department of Neurosciences, Imaging and Clinical Sciences, University "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.
Purpose: To quantitatively explore preretinal abnormal tissue (PAT) in macula-on rhegmatogenous retinal detachment (RRD) before and after surgery.
Methods: In this case-series study, PAT was detected by en-face optical coherence tomography images with custom slabs in eyes that underwent pars plana vitrectomy and SF6 for macula-on RRD.Main outcome measures were PAT area at baseline, 3-month and 6-month follow-up, and its relative change.
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