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The Influence of Relative Age and Biological Maturity on Youth Weightlifting Performance.

Pediatr Exerc Sci

January 2025

Youth Physical Development Centre, Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff,United Kingdom.

Purpose: Relative age effects and biological maturation are common biases within youth talent identification and development programs; however, their respective influence on youth weightlifting is unknown.

Method: Skeletal age, determined from ultrasonography, and competitive total loads (kg) were collected in 49 national age group weightlifters (boys: n = 24, age = 13.8 [2.

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Interplay between Skeletal Muscle Catabolism and Remodeling of Arteriovenous Fistula via YAP1 Signaling.

J Am Soc Nephrol

January 2025

Selzman Institute for Kidney Health, Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030.

Background: Arteriovenous (AV) fistulas are the preferred access for dialysis but have a high incidence of failure. This study aims to understand the crosstalk between skeletal muscle catabolism and AV fistula maturation failure.

Methods: Skeletal muscle metabolism and AV fistula maturation were evaluated in mice with chronic kidney disease (CKD).

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Background: The recently described Modified Fels wrist skeletal maturity system (mFels wrist SMS) allows for accurate skeletal maturity estimation using a single anteroposterior wrist radiograph but requires evaluation of 8 parameters. A faster method may have clinical utility in the outpatient setting.

Methods: The 8 anteroposterior wrist radiographic parameters comprising the mFels wrist SMS were analyzed in 80 children.

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Construction of a rodent neural network-skeletal muscle assembloid that simulate the postnatal development of spinal cord motor neuronal network.

Sci Rep

January 2025

Key Laboratory for Stem Cells and Tissue Engineering Ministry of Education, Guangdong Provincial Key Laboratory of Brain Function and Disease, Institute of Spinal Cord Injury, Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.

Neuromuscular diseases usually manifest as abnormalities involving motor neurons, neuromuscular junctions, and skeletal muscle (SkM) in postnatal stage. Present in vitro models of neuromuscular interactions require a long time and lack neuroglia involvement. Our study aimed to construct rodent bioengineered spinal cord neural network-skeletal muscle (NN-SkM) assembloids to elucidate the interactions between spinal cord neural stem cells (SC-NSCs) and SkM cells and their biological effects on the development and maturation of postnatal spinal cord motor neural circuits.

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Evolution of Sagittal Spinal Alignment During Pubertal Growth: A Large-Scale Study in a Chinese Pediatric Population.

J Bone Joint Surg Am

January 2025

Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People's Republic of China.

Background: Previous studies have reported normative data for sagittal spinal alignment in asymptomatic adults. The sagittal spinal alignment change in European children was recently reported. However, there is a lack of studies on the normative reference values of sagittal spinal and pelvic alignment and how these parameters change at different growth stages in Chinese children.

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