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Segmental Odontomaxillary Dysplasia: Unusual Tumoral Lesion.
Head Neck Pathol
January 2025
Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Introduction: Segmental Odontomaxillary Dysplasia (SOD) is a non-hereditary, unilateral developmental anomaly recently included in the WHO's classification of head and neck tumors.
Case Presentation: Here, we report the case of an 8-year-old boy presenting with unilateral maxillary enlargement and pain without facial asymmetry. Computed tomography revealed a hypodense area in the maxillary bone with altered bone structure and osseous expansion.
Segmental Odontomaxillary Dysplasia: Systematic Review.
Head Neck Pathol
October 2024
Oral Radiology Division, Faculdade São Leopoldo Mandic, Campinas, SP, Brazil.
Article Synopsis
- This systematic review, guided by PRISMA and registered with PROSPERO, aimed to summarize current knowledge on segmental odontomaxillary dysplasia (SOD), including its characteristics and treatment options.
- A total of 35 studies with 60 SOD cases were analyzed, showing a mean patient age of 12 years; males were more affected, and typical features included facial asymmetry, swelling, and various oral alterations.
- The review found limited treatment options reported in the studies, highlighting a scarcity of evidence on effective management strategies for SOD.
Clinicial-pathologic correlations of non-trauma related Odontodysplasia in 28 dogs: 2013-2023.
Front Vet Sci
July 2024
Department of Surgical and Radiological Sciences, University of California, Davis, Davis, CA, United States.
Odontodysplasia is an uncommon dental developmental disorder associated with enamel, dentin, pulp abnormalities, and overall tooth morphology. The affected tooth is grossly abnormal in size and contour and is commonly associated with swelling of the affected area and failure of eruption. Histologically, the enamel and dentin are hypoplastic and hypomineralized.
View Article and Find Full Text PDFAbnormal dental follicle cells: A crucial determinant in tooth eruption disorders (Review).
Mol Med Rep
September 2024
Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, P.R. China.
Article Synopsis
- The dental follicle (DF) is crucial for tooth eruption, as it regulates bone remodeling by influencing osteoblast and osteoclast activity through complex signaling pathways.
- Disruption of specific signaling pathways, such as the PTHrP-PTHrP receptor pathway, can impede osteoclast differentiation, which leads to issues with tooth eruption, alongside genetic mutations that affect DF function.
- Various genetic disorders, like Cleidocranial dysplasia and osteosclerosis, disrupt DF processes and are linked to abnormal tooth eruption, highlighting the need for more research on this topic.
PHACES syndrome and multi-regional odontodysplasia: a case report.
J Clin Pediatr Dent
May 2024
Department of Orofacial Sciences, University of California San Francisco, San Francisco, CA 94143, USA.
PHACES syndrome is an acronym for the syndromic presentation of Posterior fossa malformation, Hemangioma, Arterial anomalies, Coarctation of aorta/cardiac defects, Eye abnormalities and Sternal malformations. Infantile hemangiomas are the most common tumors of infancy. Regional odontodysplasia, commonly referred to as "ghost teeth", is a rare localized developmental malformation of enamel and dentin with varying levels of severity that results in unusual clinical and radiographic appearances of affected teeth.
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