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Background: Wound infections significantly impact morbidity, mortality, and healthcare costs globally. The Kashmir Valley's unique geographical and climatic conditions, coupled with resource constraints and antibiotic misuse, complicate managing these infections effectively. This study aimed to identify predominant bacterial pathogens in wound infections at a tertiary care hospital in Kashmir, determine their antibiotic susceptibility profiles, and estimate the prevalence of multidrug-resistant (MDR) strains.

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In this study, a simple and efficient method for synthesizing nitrogen-doped carbon quantum dots (N-CQDs) has been developed through a one-step hydrothermal process using hedyotis diffusa willd. The morphology, chemical composition, and optical properties of the resulting N-CQDs were thoroughly characterized. The synthesized N-CQDs exhibited a spherical shape with an average particle size of 4.

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Background: Healthcare-associated infections (HAI) caused by multidrug-resistant organisms have emerged as a significant global issue, posing substantial challenges to healthcare systems. Low- and intermediate-level disinfectants are extensively utilized for cleaning and disinfecting surfaces in hospitals to mitigate environmental transmission of HAI. Therefore, the need for more effective and environmentally safe disinfectants is increasing.

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Prevalence of difficult-to-treat resistance in ESKAPE pathogens in a third level hospital in Mexico.

Infect Prev Pract

March 2025

Department of Infectious Diseases, Hospital Universitario "Dr. José E. González" y Facultad de Medicina, Universidad Autónoma de Nuevo León, Mitras Centro, Monterrey, Nuevo León, CP 64460, México.

Background: Antimicrobial resistance and difficult-to-treat resistance (DTR) in ESKAPE pathogens ( and species) is a threat to human health. The aim of this study was to determine the prevalence of antimicrobial resistance and DTR rates in ESKAPE pathogens over six years in a third-level hospital from Monterrey, Mexico.

Methods: Antimicrobial susceptibility testing was determined by either disk diffusion or broth microdilution in strains from 2018 to 2023.

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Background: Periprosthetic joint infections (PJI) are one of the most devastating complications of total knee arthroplasty (TKA). Patients who have chronic kidney disease (CKD) are more vulnerable to PJI. We aimed to answer the following questions: 1) What are the commonly observed pathogens in PJI after TKA in CKD patients, and do they differ from those in non-CKD patients? and 2) What are the risk factors for PJI after TKA in CKD patients?

Methods: Patients who underwent surgery due to a chronic PJI of the TKA were retrospectively enrolled.

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