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Fixation Stability Deficits in Anisometropic Amblyopia.
Invest Ophthalmol Vis Sci
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-Sen University, Guangzhou, China.
Purpose: The purpose of this study was to investigate the relationship between fixation stability deficits in anisometropic amblyopia and various visual functions, as well as the underlying retinal structure.
Methods: All 164 patients with anisometropic amblyopia were recruited in this cross-sectional study. The contrast sensitivity function (CSF) was measured using the qCSF method, whereas the MP-3 microperimeter was used to assess fixation stability and locate the preferred retinal locus.
Peripheral Binocular Imbalance in Anisometropic and Strabismic Amblyopia.
Invest Ophthalmol Vis Sci
April 2024
Department of Psychology, Northeastern University, Boston, Massachusetts, United States.
Purpose: Individuals with amblyopia experience central vision deficits, including loss of visual acuity, binocular vision, and stereopsis. In this study, we examine the differences in peripheral binocular imbalance in children with anisometropic amblyopia, strabismic amblyopia, and typical binocular vision to determine if there are systematic patterns of deficits across the visual field.
Methods: This prospective cohort study recruited 12 participants with anisometropic amblyopia, 10 with strabismic amblyopia, and 10 typically sighted controls (age range, 5-18 years).
Associations between the cause of amblyopia and pre-treatment contrast sensitivity, stereoacuity, fixation, and nystagmus.
Heliyon
April 2024
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Purpose: To explore the association between the cause of amblyopia and pre-treatment contrast sensitivity, stereoacuity, fixation and nystagmus.
Design: Retrospective cohort study.
Methods: A retrospective review was conducted for 3408 patients with amblyopia who had not yet started amblyopia treatment utilizing a large amblyopia patient database maintained at Zhongshan Ophthalmic Centre.
Cortical Reorganization After Optical Alignment in Strabismic Patients Outside of Critical Period.
Invest Ophthalmol Vis Sci
August 2023
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong, China.
Purpose: To measure visual crowding, an essential bottleneck on object recognition and reliable psychophysical index of cortex organization, in older children and adults with horizontal concomitant strabismus before and after strabismus surgery.
Methods: Using real-time eye tracking to ensure gaze-contingent display, we examined the peripheral visual crowding effects in older children and adults with horizontal concomitant strabismus but without amblyopia before and after strabismus surgery. Patients were asked to discriminate the orientation of the central tumbling E target letter with flankers arranged along the radial or tangential axis in the nasal or temporal hemifield at different eccentricities (5° or 10°).
Evaluation of fixation characteristics in amblyopia using microperimetry.
Int Ophthalmol
September 2023
Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.
Purpose: To evaluate fixation characteristics in amblyopia using macular analyzer integrity assessment (MAIA) microperimetry and to investigate the factors affecting fixation stability.
Methods: This prospective, cross-sectional study enrolled a total of 58 amblyopic patients who were between 8 and 55 years old. Average threshold macular sensitivity (AT) and fixation characteristics were assessed using MAIA microperimetry.
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