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Clinical performance of class II MOD fiber reinforced resin composite restorations: an 18-month randomized controlled clinical trial.
BMC Oral Health
January 2025
Conservative Dentistry Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Background: In recent years, there have been suggestions for new restorative strategies that aim to effectively utilize modern adhesive technologies and protect the remaining intact tooth structure. This study was conducted to evaluate the clinical performance of fiber reinforced resin composites in restoring Class II MOD cavities over 18 months.
Methods: Forty-five participants with class II MOD cavities were randomly enrolled.
Superior Outcomes with Ultrasound-Guided Hyaluronidase for Impending Filler-Induced Facial Skin Necrosis: A Systematic Review and Pilot Meta-Analysis.
Aesthetic Plast Surg
January 2025
Department of Plastic and Reconstructive Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Background: Hyaluronidase remains the mainstay treatment for impending filler-induced facial skin necrosis. Complete resolution of impending skin necrosis following hyaluronidase injection is estimated to be around 77.8%.
View Article and Find Full Text PDFDeveloping Soluplus®-Based Microparticle Amorphous Solid Dispersions with High Drug Loading for Enhanced Celecoxib Dissolution via Electrospraying.
AAPS PharmSciTech
January 2025
Laboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, 315201, China.
Amorphous solid dispersion (ASD) is one of the most studied strategies for improving the dissolution performance of poorly water-soluble drugs, but ASDs often have low drug loadings, thereby necessitating larger dosage sizes. This study intended to create Soluplus® (SOL)-based microparticle ASDs with high drug loading (up to 60 w/w%) and long-term stability (at least 16 months) using electrospraying to enhance the dissolution of poorly water-soluble celecoxib (CEL). X-ray diffraction (XRD) and differential scanning calorimetry (DSC) analyses showed that the electrosprayed SOL-CEL microparticles were amorphous, and Fourier transform infrared spectroscopy (FTIR) data indicated the presence of hydrogen bonding between SOL and CEL in the microparticles, which helped stabilize the ASDs.
View Article and Find Full Text PDFEvaluation of bond durability of different self-adhesive bioactive restorative systems to dentin.
Sci Rep
January 2025
Conservative Dentistry Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
This study aimed to compare the bonding efficacy three bioactive self-adhesive restorative systems to dentin. A total of 80 permanent human molars were utilized in this study. The occlusal enamel was removed to exposed mid-coronal dentin; 40 molars were used for microshear bond strength testing, while the remaining molars were used for micromorphological analysis of restoration/dentin interface.
View Article and Find Full Text PDFEnhanced production, functionalization, and applications of polyhydroxyalkanoates from organic waste: A review.
Int J Biol Macromol
January 2025
Department of Chemical and Environmental Engineering and Pro-Vice-Chancellor (Planning & Resources), University of Mauritius, Reduit, Mauritius.
Polyhydroxyalkanoates (PHAs) represent a promising class of biodegradable polyesters synthesized by various microorganisms as energy storage compounds. Their versatility and environmental friendliness make them potential candidates for replacing conventional plastics across numerous applications. However, challenges such as limited mechanical properties, high production costs, and thermal instability have hindered their widespread adoption.
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