Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
digitalis toxicity
4
toxicity deal
4
digitalis
1
deal
1
Similar Publications
Nonparoxysmal junctional tachycardia associated with 3:2 Wenckebach exit block in the absence of digitalis therapy.
J Electrocardiol
December 2024
Cardiology Department, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium. Electronic address:
Article Synopsis
- - Nonparoxysmal junctional tachycardia with Wenckebach exit block is usually linked to digitalis toxicity.
- - This report highlights a case where the arrhythmia appeared without the use of digitalis medication.
- - The patient in this case had underlying structural heart disease, suggesting that other factors may trigger this type of arrhythmia.
Falling into complexity: A case of digitalis-induced fall, trauma, symptomatic bradycardia, and syncope.
J Family Med Prim Care
August 2024
Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, Delhi, India.
Article Synopsis
- - Digoxin is a cardiac medication that works by blocking the sodium potassium ATPase pump, but it has a very narrow therapeutic range, meaning the amount in the body needs to be tightly monitored.
- - Factors like age, body weight, kidney and liver function, and other medications can affect digoxin levels in the blood, increasing the risk of toxicity, which can lead to serious heart rhythm issues.
- - A case study of an elderly man showed that digoxin toxicity, exacerbated by chronic kidney disease and lack of dose adjustment, led to fainting and a mild brain injury, highlighting the dangers of improper management of digoxin in vulnerable populations.
Botrytis cinerea combines four molecular strategies to tolerate membrane-permeating plant compounds and to increase virulence.
Nat Commun
July 2024
Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands.
Article Synopsis
- Saponins are toxic compounds found in plants that help defend against pests and pathogens, with known mechanisms for fungal resistance focused on enzyme secretion.
- Researchers investigated how the fungus Botrytis cinerea tolerates specific saponins from tomato and Digitalis purpurea, discovering four mechanisms that help it overcome the toxicity.
- One novel mechanism involves enzymatic deglycosylation, while the others function in the fungal membrane, suggesting implications for understanding tolerance in both plant pathogenic fungi and potential human pathogens.
Bidirectional ventricular tachycardia due to digoxin-diuretic interaction in post-cardiac surgery patient: a case report.
Arch Peru Cardiol Cir Cardiovasc
June 2024
Hospital Regional Primero de Octubre ISSSTE, Mexico City, Mexico. Hospital Regional Primero de Octubre ISSSTE Mexico City Mexico.
Article Synopsis
- Bidirectional ventricular tachycardia (BVT) is a rare and serious heart rhythm issue marked by changes in the QRS axis with each heartbeat, often linked to digitalis toxicity.
- A 62-year-old woman who had heart surgery developed BVT after being treated with digoxin and diuretics, leading to concerns about the interaction between these medications.
- The case stresses the need for careful monitoring of digoxin levels in patients on diuretics and suggests supportive treatments if BVT occurs, like stopping digoxin and providing potassium and magnesium supplements.
"Cardiac glycosides"-quo vaditis?-past, present, and future?
Naunyn Schmiedebergs Arch Pharmacol
December 2024
Institute of Pharmacology and Toxicology, University of Würzburg, Versbacher Straße 9, 97078, Würzburg, Germany.
Article Synopsis
- Digitalis glycosides, or cardiac glycosides, are drugs that inhibit the Na/K-ATPase and are commonly used to treat heart failure and atrial fibrillation.
- Despite their effectiveness, these drugs have a narrow therapeutic range, leading to debates about their necessity and safety in these conditions.
- The article aims to review the historical context, key research findings, and the overlooked advantages and disadvantages of using digitalis glycosides in clinical practice.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!