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The influence of habitat complexity on otolith morphology and sensory capacities in Nile tilapia: A controlled experimental approach.
J Exp Biol
January 2025
Laboratory of Function and Evolutionary Morphology, FOCUS, Université de Liège, Liège, Belgique.
The inner ear of teleost fishes is known to serve both auditory and vestibular functions. Many studies have compared otoliths from different species and attempted to understand the observed differences within the light of environmental factors. However, experimental data on how otoliths could adapt are scarce.
View Article and Find Full Text PDFExperimental support for partial compensation, not matched, partner response rules in blue tits.
Behav Ecol
December 2024
Centre for Ecology and Conservation, University of Exeter, Treliever Road, Penryn, Cornwall TR10 9FE, United Kingdom.
Outcomes of theoretical models on conflict resolution between investing partners in bi-parental care systems typically predict "partial compensation" or "matched" response rules, depending on underlying assumptions. Further, although experimental tests in birds suggest that care levels by pair members are largely associated with partial compensation responses, this outcome partly depends on the type of experiment used and its effects on model assumptions. To elucidate support for both the underlying assumptions and predictions of models predicting partner compensation versus matching, we performed temporary, bi-directional brood size manipulations during late nestling provisioning in blue tits () in the French Pyrenees.
View Article and Find Full Text PDFA comprehensive allele specific expression resource for the equine transcriptome.
BMC Genomics
January 2025
Department of Population Health and Reproduction, Davis School of Veterinary Medicine, University of California, Room 4206 Vet Med3A One Shields Ave, Davis, CA, 95616, USA.
Background: Allele-specific expression (ASE) analysis provides a nuanced view of cis-regulatory mechanisms affecting gene expression.
Results: An equine ASE analysis was performed, using integrated Iso-seq and short-read RNA sequencing data from four healthy Thoroughbreds (2 mares and 2 stallions) across 9 tissues from the Functional Annotation of Animal Genomes (FAANG) project. Allele expression was quantified by haplotypes from long-read data, with 42,900 allele expression events compared.
The classification of chronic diseases has long been a prominent research focus in the field of public health, with widespread application of machine learning algorithms. Diabetes is one of the chronic diseases with a high prevalence worldwide and is considered a disease in its own right. Given the widespread nature of this chronic condition, numerous researchers are striving to develop robust machine learning algorithms for accurate classification.
View Article and Find Full Text PDFUtilization of a human Liver Tissue Chip for drug-metabolizing enzyme induction studies of perpetrator and victim drugs.
Drug Metab Dispos
January 2025
Javelin Biotech, Inc, Woburn, Massachusetts. Electronic address:
Polypharmacy-related drug-drug interactions (DDIs) are a significant and growing healthcare concern. An increasing number of therapeutic drugs on the market underscores the necessity to accurately assess new drug combinations during preclinical evaluation for DDIs. In vitro primary human hepatocytes (PHH) models are only applicable for short-term induction studies because of their rapid loss of metabolic function.
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