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Severe ARDS due to disseminated toxoplasmosis in a person with HIV successfully treated with ECMO: a case report.

Front Med (Lausanne)

January 2025

Department of Infectious Diseases, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.

Disseminated toxoplasmosis (DT) is an uncommon but severe complication associated with acquired immunodeficiency syndrome (AIDS). This case report describes the successful treatment of a 28-year-old male individual with AIDS who developed severe and life-threatening acute respiratory distress syndrome (ARDS) resulting from DT, in which extracorporeal membrane oxygenation (ECMO) was employed effectively.

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Design and optimization of IgG avidity test for differentiating acute from chronic human toxoplasmosis: A systematic review and meta-analysis.

Exp Parasitol

January 2025

Laboratory of Molecular Parasitology, Scientific Center of Zoology and Hydroecology, NASRA, 7P. Sevak St, Yerevan, 0014, Armenia; Laboratory of Zology, Research Institute of Biology, Yerevan State University, 1 Alex Manoogian, Yerevan, 0025, Republic of Armenia.

Toxoplasmosis which is caused by T. gondii, is common among humans and animals. T.

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Previous studies have reported high diversity between and within populations of Toxoplasma gondii in South America. In the present study, isolates of T. gondii from chickens were obtained from the Amazon region.

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Introduction: Tuberculosis (TB) remains the most common opportunistic infection and leading cause of death among individuals living with HIV/AIDS in Ethiopia. Its significant impact on morbidity and mortality underscores the crucial link between these two diseases. While the advent of antiretroviral therapy (ART) has led to a dramatic decline in mortality rates among HIV/AIDS patients, TB continues to pose a substantial threat.

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Article Synopsis
  • A 55-year-old woman with HIV/AIDS, adhering to her antiretroviral therapy, was hospitalized due to swallowing difficulties and swollen lymph nodes, revealing a rare case of disseminated histoplasmosis and suspected cerebral toxoplasmosis.
  • The diagnosis was confirmed through various tests, including a biopsy, (1-3) -β-glucan assay, and imaging studies.
  • This case underscores the challenges of managing opportunistic infections during immune recovery in HIV patients and the importance of vigilant monitoring and comprehensive diagnostics.
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