In 33 patients with laryngeal carcinoma operated upon with laryngectomy, a comparison has been made of the findings yielded by radiography and microlaryngoscopy and a microscopic examination using whole-organ serial sectioning. The radiographic examinations were conventional films, tomography and laryngography. Radiography supplemented in microlaryngoscopy with information of clinical importance. Surface extension of the tumour was fairly accurately assessed preoperatively whereas deep infiltration was not. Major destruction of the anterior part of the thyroid cartilage was correctly diagnosed.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1177/028418517902000511 | DOI Listing |
Naunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Otolaryngology, the First Affiliated Hospital of Xinxiang Medical University, No. 88, Jiankang Road, Xinxiang, Henan, 453100, China.
High levels of the N7 methylguanosine (m7G) methyltransferase WD repeat domain 4 (WDR4) are associated with the progression of multiple tumors, including head and neck squamous cell carcinoma. Laryngeal cancer (LC) is the second most common malignant tumor of the head and neck. However, the role of WDR4 in LC remains unclear.
View Article and Find Full Text PDFJCO Glob Oncol
January 2025
Division of Radiation Oncology, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Purpose: The incidence and survival rates of head and neck squamous cell carcinoma (HNSCC) and nasopharyngeal carcinoma (NPC) vary globally, influenced by factors such as ethnicity, lifestyle, and health care systems.
Methods: A retrospective analysis was conducted on patients with HNSCC treated between 2008 and 2020 in four major Thai academic cancer centers, using a multidisciplinary multicenter database. The study focused on the evolution of patient characteristics, survival changes, and treatment landscape alterations over time.
Int J Mol Sci
December 2024
Department of ENT, Medical University, 1000 Sofia, Bulgaria.
During the past decade, a vast number of studies were dedicated to unravelling the obscurities of non-coding RNAs in all fields of the medical sciences. A great amount of data has been accumulated, and consequently a natural need for organization and classification in all subfields arises. The aim of this review is to summarize all reports on microRNAs that were delineated as prognostic biomarkers in laryngeal carcinoma.
View Article and Find Full Text PDFActa Otorhinolaryngol Ital
December 2024
IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Objectives: Several devices have been developed to improve head and neck surgery. 3D exoscopes provide surgeons a viable alternative to microscopes. We propose our setting for transoral exoscopic oropharyngeal (TOEOS) and transoral exoscopic laryngeal surgery (TOELS).
View Article and Find Full Text PDFGene
January 2025
Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Object: N6-methyladenosine (mA), is well known as the most abundant epigenetic modification in messenger RNA, but its influence on laryngeal squamous cell carcinoma (LSCC) remains largely unexplored and poorly understood. This study was designed to explore the effects of mA on WISP1-mediated epithelial-mesenchymal transition (EMT) and tumorigenesis in LSCC.
Methods: mA methylated and expression levels of WISP1 in LSCC tumor tissues and cells were measured by MeRIP-qPCR, qRT-PCR, and western blotting.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!