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Article Synopsis
  • Xanthoma disseminatum (XD) is a rare skin condition within the group of non-Langerhans histiocytosis, presenting mainly as yellow-to-brown lesions on the face, flexures, trunk, and genital areas, and often associated with systemic issues.
  • A comprehensive review of 151 studies revealed a total of 166 cases, predominantly in females with an average diagnosis age of 35.3 years, indicating the condition's extensive extracutaneous manifestations, including those affecting the pituitary gland and oropharynx.
  • Despite various treatment options explored, including cladribine, systemic steroids, and others, there are low complete response rates, highlighting the need for further research to improve management strategies for
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Eruptive xanthomas.

N Z Med J

August 2024

Professor, Department of Dermatology, St John's Medical College, Sarjapura Road, Bangalore 560034.

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