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Hemoglobin Protects Enamel against Intrinsic Enamel Erosive Demineralization.
Caries Res
April 2024
Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Sao Paulo, Brazil.
Introduction: This study investigated the changes in the acquired enamel pellicle (AEP) proteome when this integument is formed in vivo after treatment with sugarcane-derived cystatin (CaneCPI-5), hemoglobin (HB), and a statherin-derived peptide (StN15), or their combination and then exposed to an intrinsic acid challenge. The effectiveness of these treatments in preventing intrinsic erosion was also evaluated.
Methods: Ten volunteers, after prophylaxis, in 5 crossover phases, rinsed with the following solutions (10 mL, 1 min): control (deionized water-H2O) - group 1, 0.
Proteomic profile of the acquired enamel pellicle of children with early childhood caries and caries-free children.
Eur J Oral Sci
August 2023
Department of Surgery and Orthopedics, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Acquired enamel pellicle plays an important role in the pathogenesis of early childhood caries (ECC), working as a protective interface between the tooth and the oral cavity. The aim of this cross-sectional in vivo proteomic study was to compare the acquired enamel pellicle protein profile of 3-5-year-old children with ECC (n = 10) and caries-free children (n = 10). Acquired enamel pellicle samples were collected and processed for proteomic analysis (nLC-ESI-MS/MS).
View Article and Find Full Text PDFThe histologic comparison of submandibular gland between yak and yellow cattle.
Anat Histol Embryol
July 2023
College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
The purpose of this study was to compare between the histochemical characteristics and the expression of epidermal growth factor (EGF) and it's receptor (EGFR) in the submandibular gland (SMG) of adult yaks and yellow cattle. The SMG tissues of yaks and yellow cattles were collected for histochemical, immunohistochemical (IHC), immunofluorescence (F-IHC)，real-time quantitative polymerasechain reaction (RT-qPCR) and Western blotting methods. The results showed that the striated ducts of SMG were highly developed and connected to the intercalated ducts, which were shorter and directly connected to the acini.
View Article and Find Full Text PDF[Salivary Peptide Profiling Analysis of Patients with Periodontitis and Chronic Obstructive Pulmonary Disease].
Sichuan Da Xue Xue Bao Yi Xue Ban
January 2023
Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.
Article Synopsis
- The study aimed to analyze salivary peptide profiles in patients with periodontitis (PD) and chronic obstructive pulmonary disease (COPD) to identify potential biomarkers for diagnosis and treatment.
- Involved methods included collecting saliva samples from PD patients, PD patients with COPD, and healthy controls, followed by advanced mass spectrometry techniques for peptide profiling.
- Results showed 10 peptides with significant expression differences between PD patients and those with both PD and COPD, suggesting specific peptides may serve as biomarkers for these conditions.
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