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Effect of c-Myb overexpression on osteoblastic-, odontoblastic-, and cementoblastic differentiation of primary human periodontal ligament cells.
Eur J Oral Sci
January 2025
Department of Oral Biochemistry, Institute of Oral Bioscience, School of Dentistry, Jeonbuk National University, Jeonju-si, South Korea.
The periodontal ligament (PDL) is a connective tissue, and PDL cells have a potential to differentiate into cementoblasts, osteoblasts, and gingival fibroblasts. This study investigated whether transcription factor c-Myb could induce differentiation of PDL cells for periodontal regeneration. PDL cells were isolated from extracted teeth and cultured.
View Article and Find Full Text PDFRescue of Interfragmentary Compression in Screw Stripping Failures: The Efficacy of NiTiNOL.
J Foot Ankle Surg
January 2025
Enovis Foot & Ankle, Atlanta, GA; Georgia Institute of Technology, Atlanta, GA. Electronic address:
Orthopedic screws are widely used to achieve bone reduction, compression, and construct stability. However, the relationship between insertion torque, interfragmentary compression, and fixation strength, especially when comparing standard screws with NiTiNOL/sustained dynamic compression (SDC), has not been thoroughly investigated. This study measured insertion torque, interfragmentary compression, and fixation strength for two types of headed orthopedic devices-standard and SDC-using solid foam bone replicates and cadaver validation.
View Article and Find Full Text PDFDimensions of perinatal and childhood adversities both merge and remain distinct.
Child Abuse Negl
January 2025
Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA; Program in Neuroscience, Indiana University, Bloomington, IN, USA. Electronic address:
Background: Perinatal and childhood periods are sensitive windows of development wherein adversity exposure can result in disadvantageous outcomes. Data-driven dimensional approaches that appreciate the co-occurrence of adversities allow for extending beyond specificity (individual adversities) and cumulative risk (non-specific summation of adversities) approaches to understand how the type and timing of adversities affect outcomes.
Objective: With evolving recommendations on what should be important in adversity research, we sought to establish a data-driven framework that accounts for both type and timing of adversity by (1) replicating dimensions of childhood adversities, (2) determining whether perinatal adversities form unique dimensions and (3) identifying whether adversities during the perinatal and childhood periods overlap or remain distinct.
Ubiquitination-dependent degradation of DHX36 mediated by porcine circovirus type 3 capsid protein.
Virology
January 2025
College of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, 225009, China. Electronic address:
Porcine circovirus type 3 (PCV3) is an emerging pathogen that causes porcine dermatitis, and reproductive failure. PCV3 Cap interacts with DExD/H-box helicase 36 (DHX36), a protein that functions primarily through regulating interferon (IFN)-β production. However, how the interaction between DHX36 and PCV3 Cap regulates viral replication remains unknown.
View Article and Find Full Text PDFInsights into proprioceptive acuity assessed with a dynamic joint position reproduction task.
J Electromyogr Kinesiol
January 2025
Centro Polifunzionale di Scienze Motorie, Università degli Studi di Genova, Genoa, Italy; Department of Experimental Medicine, Section of Human Physiology, Università degli Studi di Genova, Genoa, Italy.
This study investigated proprioceptive acuity using the conventional joint position reproduction (JPR) task and a modified version, the Dynamic JPR task (D-JPR), during Concentric and Eccentric muscle contractions. Seventeen participants were recruited and received a tactile stimulus indicating the position cue at Initial (INI), Intermediate (INT), and Final (FIN) phases of movements, during either the concentric or eccentric phases. After the movement, they replicated the position where they received the stimulus.
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