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Sleep disturbances and psychomotor retardation in the prediction of cognitive impairments in patients with major depressive disorder.
World J Psychiatry
October 2024
Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China.
Article Synopsis
- The study explores how symptoms of depression and anxiety, particularly concerning sleep disturbances and psychic anxiety, impact cognitive performance in patients with Major Depressive Disorder (MDD).
- Researchers conducted tests on 162 MDD patients and 142 healthy controls, finding that sleep issues negatively affected executive function and memory while psychomotor retardation influenced processing speed.
- The results indicate that psychic anxiety plays a significant role in cognitive impairments across various domains, with sleep disturbances acting as a mediator between these anxiety symptoms and cognitive performance.
Silexan in anxiety, depression, and related disorders: pharmacological background and clinical data.
Eur Arch Psychiatry Clin Neurosci
October 2024
Neurobiology Laboratory for Brain Aging and Mental Health, Psychiatric University Clinics Basel, Basel, Switzerland.
We present a narrative review of clinical trials investigating the anxiolytic and antidepressant effects of silexan, an active substance derived from lavender oil and summarize nonclinical findings from pharmacological studies supporting its therapeutic use. Six studies investigated the efficacy of the lavender oil in patients with subthreshold and generalized anxiety disorders as well as in mixed anxiety and depressive disorder (MADD). Furthermore, we present data indicating that silexan may influence sleep quality as well as anxiety or depressive disorders in individuals with post-COVID-19.
View Article and Find Full Text PDF[Mechanisms of prolonged symptoms following acute COVID-19: Some pathophysiological pathways].
Rev Mal Respir
November 2024
Service des maladies infectieuses et tropicales, CHU d'Angers, 4, rue Larrey, 49100 Angers, France. Electronic address:
Introduction: Following the Omicron wave in early 2022, an estimated 60-70% of the French population was infected with the SARS-CoV-2 virus. One out of ten infected subjects could have persistent symptoms three months after infection, representing a public health challenge.
Current State Of Knowledge: The persistent symptoms may be secondary to diverse entities with distinct mechanisms.
Thyroid function, renal function, and depression: an association study.
Front Psychiatry
December 2023
Department of Neurology, Minhou Country Hospital, Fuzhou, China.
Objective: To investigate the correlations between thyroid function, renal function, and depression.
Methods: Clinical data of 67 patients with Major depressive disorder (MDD) and 36 healthy control subjects between 2018 and 2021 were collected to compare thyroid and renal function. Thyroid and renal functions of depressed patients were then correlated with the Hamilton Depression Rating Scale (HAMD) and the Hamilton Anxiety Rating Scale (HAMA).
Depression and anxiety mediate the relationship between the retrospectively measured symptoms of premenstrual disorders and negative but not positive psychotic-like experiences.
Sci Rep
October 2023
Institute of Psychology, Jagiellonian University, Kraków, Poland.
The aim of this study was to examine the relationship between retrospectively measured premenstrual symptoms and subclinical forms of positive and negative psychotic symptoms (psychotic-like experiences; PLEs). It was hypothesised that subjective intensity of the symptoms of premenstrual disorders predicts PLEs frequency and that this relationship is mediated by anxiety and depression. The study sample comprised 108 non-clinical subjects.
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