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Cardiovascular risks of Asian patients on androgen-receptor-targeted agents for prostate cancer: a systematic review and meta-analysis.
Prostate Int
December 2024
Department of Urology, National University Hospital, National University Health System, Singapore.
Background: Prostate cancer is now one of the most prevalent cancers in men in Asia. As the average life expectancy of Asian males with prostate cancer increases with the availability of treatment options, the possible risk of cardiac-related adverse effects arising from androgen-receptor-targeted agents (ARTAs) may be increased due to the greater exposure. We aim to perform a meta-analysis on the incidence of cardiac-related adverse events in Asian patients with prostate cancer treated with ARTAs.
View Article and Find Full Text PDFImproving diagnosis of primary aldosteronism through education: a modified Delphi study to identify key learning points.
Ther Adv Chronic Dis
December 2024
Monash University, Clayton, VIC, Australia.
Background: Primary aldosteronism (PA) is the most common endocrine cause of secondary hypertension and can be effectively managed, or even cured, with targeted treatment. Despite this, it remains largely undiagnosed leaving a significant patient population with resistant hypertension and modifiable cardiovascular risk.
Objective: To determine expert consensus on key information about PA that should ideally be taught to medical students as a step toward improving the detection of this common, underdiagnosed, and often easily treated condition.
Bullet characterization using Photon-Counting detector CT: A phantom study with intact bullets.
Eur J Radiol
December 2024
Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre+, PO Box 5800, 6202 AZ Maastricht, the Netherlands; Mental Health and Sciences (MHeNs) Research Institute, Maastricht University, PO Box 616, 6200 MD Maastricht, the Netherlands.
Objectives: Photon-counting detector CT (PCD-CT) is expected to substantially improve and expand CT-imaging applicability due to its intrinsic spectral capabilities, increased spatial resolution, reduced electronic noise, and improved image contrast. The current study aim is to evaluate PCD-CT efficacy in characterizing bullets based on their dimensions, shape, and material composition.
Materials And Methods: This is an observational phantom study examining 11 unfired, intact bullets of various common calibers, placed in ballistic gelatin.
Effects of Gestational Diabetes Mellitus on Fetal Cardiac Morphology.
Med Sci (Basel)
December 2024
Department of Perinatology, Ege University, İzmir 35000, Turkey.
Objective: This study aims to investigate the possible effects of gestational diabetes mellitus (GDM) on fetal heart structure and the relationship of this effect with maternal blood sugar control.
Materials And Methods: In this cross-sectional study, 19 women with GDM at 24-36 weeks of gestation (case group) and 21 healthy pregnant women at the same weeks of gestation (control group) were examined. Fetal heart structure was evaluated by ultrasonography; interventricular septum (IVS) thickness, right and left ventricular sphericity indices, global sphericity index (GSI) and cardio-thoracic ratio were also measured.
Spotlight on YAP: Unlocking New Insights to Overcome the Barriers to Heart Regeneration.
Circulation
January 2025
Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA (N.V., R.T.L.).
This editorial refers to “Microtubules Sequester Acetylated YAP in the Cytoplasm and Inhibit Heart Regeneration” by Liu . and “YAP Overcomes Mechanical Barriers to Induce Mitotic Rounding and Adult Cardiomyocyte Division” by Morikawa
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