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Left Atrial Papillary Fibroelastoma Mimicking Myxoma.
JACC Case Rep
January 2025
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Papillary fibroelastomas (PFEs) followed by cardiac myxomas (CM) are the 2 most common primary benign cardiac tumors. Although typically asymptomatic, they can manifest with nonspecific symptoms such as dyspnea and dizziness or more acute manifestations such as embolic events. We describe an unusual location of a PFE typically seen with a CM.
View Article and Find Full Text PDFTreatment with BRAF/MEK: inhibitors in mutant BRAF V600E papillary craniopharyngioma.
Endocr Oncol
January 2024
Department of Oncology, Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden.
Summary: Craniopharyngiomas (CPs) are rare brain epithelial tumours arising in the suprasellar region, infiltrating adjacent areas causing visual loss, panhypopituitarism, cognitive deficits and morbid obesity. Papillary CPs (PCPs) harbour in 94% BRAF mutation cases. Two patients with PCP and BRAF V600E mutations but with different tumour status were treated with BRAF and MEK inhibitors.
View Article and Find Full Text PDFAtypical Location of Papillary Fibroelastoma in a Patient With Significant Oncologic History.
JACC Case Rep
December 2024
Division of Cardiac Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
This report discusses the case of a 57-year-old woman with a history of breast cancer and gastric cancer, germline CDH1 gene mutation, who presented to the hospital with syncope. Diagnostic workup revealed a mass in the right ventricular outflow tract. Transcatheter biopsy suggested papillary fibroelastoma, which was confirmed with surgical pathology.
View Article and Find Full Text PDFPercutaneous Removal of Cardiac Papillary Fibroelastomas.
JACC Case Rep
December 2024
Department of Cardiovascular Diseases, Mayo Clinic, Jacksonville, Florida, USA.
Papillary fibroelastomas (PFEs) are primary cardiac tumors associated with significant embolic risk. Surgical excision or medical therapy with antiplatelets and/or anticoagulants have been the treatment options for symptomatic patients. This paper reports our early experiences of percutaneous removal of PFE using mechanical aspiration techniques.
View Article and Find Full Text PDFPapillary Fibroelastoma of Aortic Valve: An Echocardiographic Correlation With Surgery and Anatomopathology.
JACC Case Rep
December 2024
Department of Cardiology, Valdivia Hospital, School of Medicine Austral University, Valdivia, Chile.
This case presents a 69-year-old woman with a previous history of arterial hypertension. A transthoracic echocardiogram was requested in the context of shortness of breath with great exercise. Incidentally, at the aortic valve level, a mobile mass suggestive of papillary fibroelastoma was visualized.
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