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Background: When antispasmodics are unavailable, the periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER; called BLADE by Siemens Healthineers) or half Fourier single-shot turbo spin echo (HASTE) is clinically used in gynecologic MRI. However, their imaging qualities are limited compared to Turbo Spin Echo (TSE) with antispasmodics. Even with antispasmodics, TSE can be artifact-affected, necessitating a rapid backup sequence.

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Article Synopsis
  • - Researchers developed a new method to reduce thermal conductivity in materials, which is crucial for applications like thermoelectrics, by manipulating the dynamics of guest molecules within a structure.
  • - By applying pressure to methane hydrate, they found that enhanced interactions between rotating molecules and lattice vibrations lead to significant decreases in thermal conductivity, nearly tripling the suppression effect.
  • - This technique highlights a universal approach to control heat transport in various material systems by optimizing the strength of interactions between rotating molecules and the lattice.
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Deep Learning-Enhanced Accelerated 2D TSE and 3D Superresolution Dixon TSE for Rapid Comprehensive Knee Joint Assessment.

Invest Radiol

August 2024

From the imec-Vision Lab, Department of Physics, University of Antwerp, Antwerp, Belgium (C.S., Q.B., J.S., B.J.); Siemens Healthcare NV/SA, Groot-Bijgaarden, Belgium (C.S., T.J.); Department of Radiology, Antwerp University Hospital, Antwerp, Belgium (F.B., F.V., A.S., P.V.D.); and MIRA, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium (A.S., P.V.D.).

Article Synopsis
  • - The study aimed to assess the effectiveness of advanced deep learning techniques in speeding up knee MRI scans while maintaining image quality and diagnostic accuracy, comparing a new 4-fold accelerated protocol and a 3D superresolution reconstruction against a standard 2-fold accelerated method.
  • - Researchers conducted MRI scans on 19 adult participants using three different protocols in a single session, resulting in over 21,000 images that were evaluated for quality and diagnostic confidence by three readers, including two specialized radiologists.
  • - Statistical analysis was performed to compare the protocols, focusing on image quality and the detection of knee injuries, with the outcomes assessed using Likert scales for both anatomical visibility and confidence in diagnosis.
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Generalized 3D registration algorithm for enhancing retinal optical coherence tomography images.

J Biomed Opt

June 2024

The University of British Columbia, School of Biomedical Engineering, Faculty of Medicine and Applied Science, Vancouver, British Columbia, Canada.

Significance: Optical coherence tomography (OCT) has emerged as the standard of care for diagnosing and monitoring the treatment of various ocular disorders due to its noninvasive nature and volumetric acquisition capability. Despite its widespread applications in ophthalmology, motion artifacts remain a challenge in OCT imaging, adversely impacting image quality. While several multivolume registration algorithms have been developed to address this issue, they are often designed to cater to one specific OCT system or acquisition protocol.

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Cellular RNA is asymmetrically distributed in cells and the regulation of RNA localization is crucial for proper cellular functions. However, limited chemical tools are available to capture dynamic RNA localization in complex biological systems with high spatiotemporal resolution. Here, we developed a new method for RNA proximity labeling activated by near-infrared (NIR) light, which holds the potential for deep penetration.

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