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Tick-Borne Encephalitis Virus Infection in a Two-Year-Old Child Returning from Switzerland (July-August 2023): Is It Time for TBE Immunization of Serbian Travelers?
Pathogens
November 2024
Diagnostics and Laboratory Research Task Force, Balkan Association for Vector-Borne Diseases, 21000 Novi Sad, Serbia.
Tick-borne encephalitis (TBE) is a vaccine-preventable viral infection that poses significant public health challenges, particularly in regions where tick-borne diseases are endemic. This case report describes a 2-year-old boy with confirmed abortive TBEV infection following a tick bite during travel to Switzerland. The patient developed fever and mild symptoms but did not exhibit central nervous system involvement.
View Article and Find Full Text PDFDecoding recurrent pregnancy loss: insights from comparative proteomics studies.
Biol Reprod
January 2025
Research Centre for Genetic Engineering and Biotechnology "Georgi D Efremov", Macedonian Academy of Sciences and Arts, Krste Misirkov 2, 1000 Skopje, North Macedonia.
Article Synopsis
- * This review evaluates existing comparative proteomics studies on samples from women with RPL, focusing on analyzed materials, biomarker candidates, and pathways linked to the condition.
- * It highlights the most identified biomarkers, discusses bioinformatics data, and explores future therapeutic strategies to address RPL more effectively.
Increased prevalence of negative pregnancy and fetal outcomes in women with primary adrenal insufficiency. A systematic review and meta-analysis.
Endocrine
December 2024
Unit of Endocrinology, Diabetes Mellitus and Metabolism, "Aretaieion" Hospital, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Article Synopsis
- Maternal primary adrenal insufficiency (PAI) during pregnancy, caused by Addison disease or congenital adrenal hyperplasia, is rare, and there's limited research on its effects on fetal and neonatal outcomes.
- A systematic review and meta-analysis examined 31 studies, 11 of which were quantitatively analyzed, focusing on outcomes like spontaneous abortion, preterm birth, and small for gestational age (SGA) neonates.
- Results showed higher rates of spontaneous abortions (18%), preterm births (11% overall), and SGA neonates (8% overall) in women with PAI compared to controls, although fetal birth weights remained normal across all groups studied.
Domestic Violence in Pregnancy during the Pandemic Era: a Systematic Review.
Maedica (Bucur)
June 2024
Department of Midwifery, University of West Attica, Agiou Spyridonos 28, 12243 Egaleo, Greece.
Introduction: Women, and mainly pregnant ones, have been always highly vulnerable to domestic violence/intimate partner violence (DV/IPV) throughout their lives. Covid-19 pandemic brought new unprecedented living conditions that raised the rates of DV during pregnancy. Investigating the association between Covid-19 and DV in pregnant women may help government and community groups seeking to reduce DV/IPV in vulnerable populations in order to better understand the prevalence of this phenomenon and its associated factors and thus find ways to ensure control and stop domestic violence, as the society and health care systems are still disorganized in the way they deal with the DV against pregnant women.
View Article and Find Full Text PDFProteomics Analysis of Human Chorionic Villi Reveals Dysregulated Pathways That Contribute to Recurrent Pregnancy Loss.
Proteomics Clin Appl
November 2024
Research Centre for Genetic Engineering and Biotechnology "Georgi D Efremov", Macedonian Academy of Sciences and Arts, Skopje, North Macedonia.
Purpose: Recurrent pregnancy loss (RPL) represents a common disorder with consequences on family and society. As more than half of the RPL cases do not have a clearly identified cause, uncovering the mechanisms behind the idiopathic RPL is urgently needed.
Experimental Design: Using label-free data-independent LC-MS/MS acquisition coupled with ion mobility, we compared the proteome of chorionic villi from 13 RPL cases with 10 age and gestational week-matched elective pregnancies.
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