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Advancing Adult-Acquired Flatfoot Deformity Treatment: Enhanced Biomechanical Support Through Graphene Oxide-Integrated Bioengineered Grafts Tested In Silico.
J Funct Biomater
November 2024
Department of Biomedical Engineering, Universidad de Los Andes, Bogotá 111711, Colombia.
Adult-Acquired Flatfoot Deformity (AAFD) is a progressive orthopedic condition causing the collapse of the foot's medial longitudinal arch, often linked with injuries to the plantar arch's passive stabilizers, such as the spring ligament (SL) and plantar fascia. Conventional treatment typically involves replacing the SL with synthetic material grafts, which, while providing mechanical support, lack the biological compatibility of native ligaments. In response to this shortcoming, our study developed an electrospun, twisted polymeric graft made of polycaprolactone (PCL) and type B gelatin (GT), enhanced with graphene oxide (GO), a two-dimensional nanomaterial, to bolster biomechanical attributes.
View Article and Find Full Text PDFInnovative surgical treatment of tarsal coalition in flatfoot: Resection and interposition of synthetic membrane, flexible bioresorbable polymers film, as adhesion barrier and subtalar arthroeresis. Up to nine years follow-up.
Foot Ankle Surg
October 2024
U.O.C Ortopedia e Traumatologia Pediatrica, ASST Gaetano Pini/CTO, Piazza Cardinal Ferrari 1, 20122 Milan, Italy.
Tarsal coalition can be a long term severely disabling condition. For symptomatic cases with flatfoot surgical resection of coalition and subtalar arthroeresis represents the most common treatment. Literature reports variable outcomes and recurrence.
View Article and Find Full Text PDFStudy on the balance and gait characteristics of subjects with generalized joint hypermobility residing in high-altitude using wearable devices: a cross-sectional study.
BMC Musculoskelet Disord
October 2024
Key Laboratory of Exercise and Health Sciences of the Ministry of Education, Shanghai University of Sport, Shanghai, China.
Article Synopsis
- This study aimed to examine balance and gait functions in individuals with Generalized Joint Hypermobility (GJH) living in high-altitude regions, specifically Linzhi, Tibet.
- It involved 61 university students, comparing 28 with GJH to 33 healthy controls, and utilized a wearable system to assess their balance and walking capabilities.
- Results showed that GJH subjects had significant balance deficits and reduced gait metrics compared to healthy subjects, indicating a need for targeted training and prevention strategies for this population.
An overview of the risk factors for producing fifth metatarsal fracture in sports activities: A systematic review.
J Foot Ankle Res
December 2024
Group of Research in Sport Science (INCIDE), Department of Physical Education and Sport, Universidade da Coruña, A Coruña, Spain.
Article Synopsis
- The fifth metatarsal fracture is a common foot injury in sports, influenced by intrinsic factors like foot type and bone density, as well as extrinsic factors like sports activities and playing surfaces.
- A literature review analyzed studies to find the key risk factors associated with this injury, identifying that soccer, critical maneuvers, and foot biomechanics are significant contributors.
- Understanding these risk factors is essential for developing preventive measures and effective treatment strategies for athletes at risk of this injury.
The causality between rheumatoid arthritis and postural deformities: bidirectional Mendelian randomization study and mediation analysis.
Front Immunol
October 2024
Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Beijing, China.
Article Synopsis
- The study investigates the causal relationship between rheumatoid arthritis (RA) and postural deformities, specifically hallux valgus and flat foot, using Mendelian randomization analysis in European populations.
- Summary data from the IEU OpenGWAS project and Finngen database were utilized, employing methods like inverse variance weighting to evaluate causality and ensuring no significant horizontal pleiotropy was present.
- Results indicate a causal link between RA, hallux valgus, and flat foot, with hallux valgus acting as a mediator in the relationship between RA and flat foot, highlighting the need for targeted interventions in affected patients.
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