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The efficacy of InterRhythmic care for depression: A randomized control trial.
J Psychiatr Res
November 2024
General Psychiatry Department, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China; Mental Health Branch, China Hospital Development Institute, Shanghai Jiao Tong University, Shanghai, 20030, China; Shanghai Key Laboratory of Psychotic disorders, Shanghai, 20030, China. Electronic address:
Objective: This study investigates the efficacy of an InterRhythmic Care (IRC) for major depressive disorder (MDD). There is a lack of clinical studies on its effect on depression.
Methods: In this eight-week, randomized, single-blind, controlled trial, 120 patients with MDD were randomly assigned to receive IRC or Internet general psychoeducation (IGP).
White matter brain-age in diverse forms of epilepsy and interictal psychosis.
Sci Rep
August 2024
Department of Radiology, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo, 187-8551, Japan.
Article Synopsis
- Abnormal brain aging is linked to epilepsy, with a focus on how white matter tracts, which connect different brain regions, might play a key role.
- Researchers conducted a study using brain diffusion tensor imaging on 257 epilepsy patients and 429 healthy individuals to develop a model for predicting brain age.
- Results showed that most types of epilepsy exhibited significantly increased brain age compared to their chronological age, with temporal lobe epilepsy and those with comorbid psychosis showing particularly pronounced effects.
Electroconvulsive Therapy for Psychogenic Polydipsia and Hyponatremia in Chronic Schizophrenia: A Case Report and Literature Review.
J ECT
August 2024
From the Department of Psychiatry, Albany Medical College, Albany, NY.
Compulsive drinking of excessive quantities of water, called psychogenic polydipsia (PP), is a challenging complication of chronic psychotic disorders, which can lead to hyponatremia and downstream morbidity or mortality. Treatments include behavioral modifications such as free water restriction, medications to modify free water excretion, and psychotropic medications to target psychotic symptoms. However, in many cases, these options remain ineffective and/or intolerable, necessitating chronic institutionalization with poor patient quality of life.
View Article and Find Full Text PDF[Fluvoxamine in the treatment of anxiety-depressive spectrum disorders].
Zh Nevrol Psikhiatr Im S S Korsakova
July 2024
Peoples' Friendship University of Russia, Moscow, Russia.
The RSCI and PubMed search databases have requested publications over the past 40 years on the search queries «fluvoxamine», «anxiety-depressive disorders», «anxiety», «depression», «comorbidity», devoted to the effectiveness of fluvoxamine in various variants of disorders of the anxiety-depressive spectrum, anxiety depressions. The data of the above studies indicate that fluvoxamine (Zovart San) in doses of 50-300 mg / day is a highly effective remedy for the treatment of not only anxiety depressions and genesis (psychogenic, organic, mixed, autochthonous-endogenous) and severity (up to psychotic), but also a wider range of anxiety-depressive disorders, including adaptation disorders, obsessive-compulsive disorder, somatized, dysmorphic, insomniac symptom complexes and eating disorders. A wide range of clinical effects of fluvoxamine is due to its main and additional mechanisms of action: blockade of serotonin reuptake, 1-agonist activity and the effect on the metabolism of melatonin and neurosteroids catabolism.
View Article and Find Full Text PDFPost-Traumatic Stress-Disorder in Epilepsy: Meta-analysis of current evidence.
Epilepsy Behav
August 2024
Neurology, Epilepsy and Movement Disorders Unit, Bambino Gesù Children's Hospital, IRCCS, Full Member of European Reference Network on Rare and Complex Epilepsies, EpiCARE, Rome, Italy.
Epilepsy, a chronic neurological condition characterized by unpredictable seizures, poses considerable challenges, including disability, stigma, and increased mortality. Psychiatric comorbidities are prevalent in 20-30% of epilepsy patients, notably mood or anxiety disorders, psychotic symptoms, and personality disorders. Trauma and childhood adversities are pivotal risk factors for psychopathology, yet the link between Post-Traumatic Stress Disorder (PTSD) and epilepsy remains underexplored.
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