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Comparison of the efficacy of LTCBDE and LCBDE for common bile duct stones: a systematic review and meta-analysis.
Front Surg
January 2025
Department of Hepatobiliary Surgery, Affiliated Hospital of Chengde Medical University, Chengde, Hebei Province, China.
Background: The choice of surgical methods for common bile duct stones (CBDS) is controversial. The aim of this study was to compare the safety and efficacy of laparoscopic transcystic common bile duct exploration (LTCBDE) and laparoscopic common bile duct exploration (LCBDE).
Methods: Relevant literature published before March 30, 2023 in PubMed, Web of Science, Embase, and Cochrane was searched to screen studies comparing LTCBDE and LCBDE.
'They went for the test together but came back separately': a constructivist grounded theory perspective on male engagement in antenatal HIV testing in Bamenda, Cameroon.
BMC Pregnancy Childbirth
January 2025
Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.
Introduction: Male engagement in HIV testing during pregnancy significantly contributes towards the prevention of maternal seroconversion and paediatric HIV acquisition. Despite this, men especially the male partners of pregnant women have been consistently missing in the HIV prevention cascade. The factors accounting for sub-optimal levels in male engagement intersect but reasons for this are poorly understood.
View Article and Find Full Text PDFOperating Characteristics of the Simulated Healthy Participant Approach in Impaired Clearance Studies.
AAPS J
January 2025
Pharmacometrics and Systems Pharmacology, Pfizer, Groton, Connecticut, U.S.A..
Minimizing harm is a cornerstone of ethical research practices. A drug that has undergone extensive clinical pharmacological testing in healthy participants (HPs) and a diverse selection of patients can be described with a sufficiently predictive population pharmacokinetic (PopPK) model. In impaired clearance trials, recruitment is minimized and underpowered for all but major exposure differences.
View Article and Find Full Text PDFComparison of Efficacy and Safety of Endoscopic Retrograde Cholangiopancreatography in Choledocholithiasis Patients at Different Age Groups: A Meta-Analysis.
Turk J Gastroenterol
January 2025
Department of Maternity, Xijing 986 Hospital, Air Force Medical University, Xi'an, China.
Background/aims: Endoscopic retrograde cholangiopancreatography (ERCP) is often recommended as the first choice for the treatment of choledocholithiasis in the elderly. This study aims to investigate the efficiency and safety of ERCP in choledocholithiasis patients of different age groups.
Materials And Methods: Study searching was performed in the PubMed, Embase, Web of Science, and Cochrane Library databases from the inception to August 2024.
The Effect of Gallic Acid on the Alleviation of the Chemotherapy-Induced Myelosuppression.
Curr Med Chem
January 2025
Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing, 400014, P.R. China.
Objective: This study aims to investigate the effect of Gallic Acid (GA) on the alleviation of chemotherapy-induced bone marrow suppression, with a comparison to Diyu sheng bai tablets (DYSB) and RhG-CSF.
Methods: A mouse model of bone marrow suppression was established in BALB/c mice using intraperitoneal injections of cyclophosphamide (CTX). All procedures were performed after obtaining ethical clearance from the institutional animal ethics committee.
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