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Error compensation in a redundant system during 'failure' of individual motor elements.
Exp Brain Res
January 2025
Department of Kinesiology, Michigan State University, 308 W Circle Dr, East Lansing, USA.
A characteristic feature of redundancy in the motor system is the ability to compensate for the failure of individual motor elements without affecting task performance. In this study, we examined the pattern and variability in error compensation between motor elements during a virtual task. Participants performed a redundant cursor control task with finger movements.
View Article and Find Full Text PDFBackground: Kirschner wire (K-wire) and intramedullary (IM) screw fixation are accepted techniques for treatment of unstable proximal phalanx fractures, but comparative reports are lacking. This study aimed to evaluate early clinical outcomes following treatment with K-wire or IM fixation.
Methods: A retrospective review of all proximal phalanx fractures treated surgically at a single center by multiple surgeons was performed from May 1, 2019 to March 1, 2024.
Short-term effects of brief stair climbing interruptions on postprandial hyperglycemia during prolonged sitting: a randomized cross-over trial.
Sci Rep
January 2025
Department of Community Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Prolonged sitting can negatively impact postprandial glucose levels and cognitive function. While short bouts of stair climbing are thought to mitigate these risks, the findings remain inconclusive. The present study aimed to explore the effects of stair climbing bouts on postprandial glucose and cognitive functions during prolonged sitting.
View Article and Find Full Text PDFUnidirectional MCM translocation away from ORC drives origin licensing.
Nat Commun
January 2025
Macromolecular Machines Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.
The MCM motor of the eukaryotic replicative helicase is loaded as a double hexamer onto DNA by the Origin Recognition Complex (ORC), Cdc6, and Cdt1. ATP binding supports formation of the ORC-Cdc6-Cdt1-MCM (OCCM) helicase-recruitment complex where ORC-Cdc6 and one MCM hexamer form two juxtaposed rings around duplex DNA. ATP hydrolysis by MCM completes MCM loading but the mechanism is unknown.
View Article and Find Full Text PDFNo significant relationship found between spontaneous motor tempo, heartbeat, and individual alpha frequency: an analysis of internal tempos.
Sci Rep
January 2025
Department of Life Sciences, The University of Tokyo, Tokyo, Japan.
Many theories of time perception propose the existence of an internal pacemaker, and studies across behavioral, physiological, and neuroscience fields have explored this concept. Specifically, Spontaneous Motor Tempo (SMT), the most comfortable and natural tapping tempo for each individual, is thought to reflect this internal pacemaker's tempo. Changes in heart rate are also linked to time estimation, while Individual Alpha Frequency (IAF), the peak in the alpha range (8-13 Hz) observed in EEG, is reported to reflect the brain's temporal processing.
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